Gastroenterology:夹子闭合与较大结肠病变术后出血风险

2019-11-05 MedSci MedSci原创

夹子闭合可减少较大无蒂结直肠病变患者术后的延迟出血风险

近日研究人员评估了2cm以上非蒂结直肠病变患者接受结肠内窥镜粘膜切除术(EMR)后采用夹子封闭对延迟出血风险的影响。

235名连续接受EMR治疗的患者参与研究,患者因较大的无蒂病变而有较高的延迟出血风险,患者随机接受11 mm穿透性夹(治疗组,n=119)或不加夹组(对照组,n=116)。研究的主要终点为延迟出血的患者比例。

在夹子组中,68例(57%)病例完成完全闭合,33例(28%)病例部分闭合,18例(15%)病例未闭合。对照组14例(12.1%)患者和夹子组6例(5%)患者出现延迟出血(绝对风险差异,夹子组减少7%)。在完成夹闭后,仅有1例(1.5%)延迟出血(绝对风险降低10.6%)。

研究认为,夹子闭合可减少较大无蒂结直肠病变患者术后的延迟出血风险。

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