Circulation:对于普通健康中年男性,心肺适应性越好,心血管意外风险越低

2018-05-02 MedSci MedSci原创

一篇极具说服力的文献表明冠状动脉钙化(CAC)和心肺适应性(CRF)都是心血管疾病(CVD)事件的独立预测因子。但目前我们对CRF和CAC关于CVD风险的相互联系知之甚少。CAC高时,CRF高相比CRF低与CVD事件减少相关。Nina B. Radford等人故开展一项研究,在CAC负担增加的背景下,对CRF持续水平对CVD风险的影响进行评估。研究人员共研究了8425位无临床CVD的男性,其于19

一篇极具说服力的文献表明冠状动脉钙化(CAC)和心肺适应性(CRF)都是心血管疾病(CVD)事件的独立预测因子。但目前我们对CRF和CAC关于CVD风险的相互联系知之甚少。CAC高时,CRF高相比CRF低与CVD事件减少相关。Nina B. Radford等人故开展一项研究,在CAC负担增加的背景下,对CRF持续水平对CVD风险的影响进行评估。

研究人员共研究了8425位无临床CVD的男性,其于1998年-2007年间进行预防性医学检查,包括CRF和CAC的客观检测。平均随访8.4年,共发生383例CVD事件。

CVD事件发生量,随CAC的增加而增加,随CRF的增加而减少。根据CAC水平校正后(0、1-99、100-399、≥400),CRF的MET每增加一级,CVD事件风险就降低11%(危险比 0.89;95% CI 0.84-0.94)。同时考虑CAC和CRF时,在所有CAC组中,持续CRF和CVD发病率的关联更为明显。

在本纳入大量普通健康男性的队列中,研究结果表明对于所有CAC水平,CRF越高,CVD风险则越小。

原始出处:

https://doi.org/10.1161/CIRCULATIONAHA.117.032708

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    2018-05-14 aids222
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    2018-05-02 天地飞扬

    了解一下.谢谢分享!

    0

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    2018-05-02 忠诚向上

    好好学习天天向上

    0

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