ANN SURG:建立风险评分预测巴雷特食管进展

2018-03-25 MedSci MedSci原创

内镜治疗可以有效的治疗巴雷特食管且并发症发生率很低。但是那些患者需要接受治疗一直存在争议。目前已知的危险因素不足以准确预测哪些患者会进展为异常发育或腺癌。ANN SURG近期发表了一篇文章,报道了一种可以有效预测巴雷特食管进展为异常发育或食管腺癌的评分工具。

内镜治疗可以有效的治疗巴雷特食管且并发症发生率很低。但是那些患者需要接受治疗一直存在争议。目前已知的危险因素不足以准确预测哪些患者会进展为异常发育或腺癌。ANN SURG近期发表了一篇文章,报道了一种可以有效预测巴雷特食管进展为异常发育或食管腺癌的评分工具。

作者回顾性收集了13年间巴雷特食管的数据。使用多元logistic回归模型预测进展。建立了进展风险评分。队列共包括2591例巴雷特食管患者,其中133例进展为异常发育或腺癌。多因素分析表明5个因素与风险评分增加有关(年龄≥70,男性,未接受质子泵抑制剂治疗,病变大于3cm以及食管念珠菌病史)。使用这一模型,作者建立了0-8的简化进展风险评分系统。ROC分析表明3分及以上灵敏度为70%,特异度为79%。3分及以上的患者比值比为9.04。

文章最后认为,该研究结果表明巴雷特食管风险评分具有鉴别进展为发育异常或腺癌的能力。巴雷特食管风险评分可以用于临床指导巴雷特食管患者的治疗决策。

原始出处:

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    2018-03-27 owlhealth

    不错耶.学习了

    0

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    2018-03-27 zhouqu_8
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    2018-03-26 Ramsey

    学习了

    0

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    2018-03-26 owlhealth

    不错耶.学习了

    0

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    2018-03-25 哈哈869

    学了

    0

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    2018-03-25 wqkm

    ^_^^_^^_^

    0

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