消化

订阅

MedSci主页 / 所有栏目 / 消化

Pediatrics：乳酸杆菌治疗儿童腹泻

2015-01-14 MedSci MedSci原创译

乳酸杆菌腹泻呼吸道感染安慰剂双盲随机对照
关注

为了研究每日服用罗伊乳酸杆菌DSM 17938 对降低腹泻频次、持续时间和其他疾病结局的作用，来自墨西哥的研究者对当地4个日托中心对6-36个月儿童展开一项双盲的随机对照研究。总共纳入了所有护理中心的健康儿童，随机分组进行双盲、安慰剂对照研究。其中有168名儿童使用罗伊乳酸杆菌DSM 17938，168名儿童口服安慰剂，研究共持续了3个月，随后进行长达3个月的随访。结果发现，在3个月和6个月时，罗

为了研究每日服用罗伊乳酸杆菌DSM 17938 对降低腹泻频次、持续时间和其他疾病结局的作用，来自墨西哥的研究者对当地4个日托中心对6-36个月儿童展开一项双盲的随机对照研究。总共纳入了所有护理中心的健康儿童，随机分组进行双盲、安慰剂对照研究。其中有168名儿童使用罗伊乳酸杆菌DSM 17938，168名儿童口服安慰剂，研究共持续了3个月，随后进行长达3个月的随访。结果发现，在3个月和6个月时，罗伊乳酸杆菌DSM 17938显著降低了腹泻的频次、持续时间以及呼吸道感染性疾病的发生。另外，缺课次数、抗生素使用频率、患儿父母工作请假次数、就医次数等，结果都是实验组比安慰剂组要好。成本效益分析发现，罗伊乳酸杆菌治疗组比安慰剂组的成本低。两组实验都没有发现不良事件。研究结果表明，健康儿童每天去日托中心，服用罗伊乳酸杆菌DSM 17938能够显著降低腹泻的频次和持续时间以及呼吸道疾病的感染，并且为社区医疗降低了成本。原始出处： Gutierrez-Castrellon, P., et al., Diarrhea in preschool children and Lactobacillus re

版权声明：
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1637022, encodeId=8bc7163e02276, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Jul 22 20:47:00 CST 2015, time=2015-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958403, encodeId=66741958403d9, content=<a href='/topic/show?id=766713993a1' target=_blank style='color:#2F92EE;'>#Pediatric#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13993, encryptionId=766713993a1, topicName=Pediatric)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Thu Nov 19 08:47:00 CST 2015, time=2015-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725728, encodeId=433d1e2572863, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Thu Apr 16 12:47:00 CST 2015, time=2015-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1513606, encodeId=9b65151360683, content=<a href='/topic/show?id=7e1c23814ea' target=_blank style='color:#2F92EE;'>#乳酸杆菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23814, encryptionId=7e1c23814ea, topicName=乳酸杆菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=391710575663, createdName=陆成振, createdTime=Fri Jan 16 04:47:00 CST 2015, time=2015-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=14319, encodeId=629114319f0, content=吗咪爱有效的, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=223.104.5.**, createdTime=Wed Jan 14 15:48:00 CST 2015, time=2015-01-14, status=1, ipAttribution=)]
    2015-07-22 ms9608593228839890

    #DIA#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1637022, encodeId=8bc7163e02276, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Jul 22 20:47:00 CST 2015, time=2015-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958403, encodeId=66741958403d9, content=<a href='/topic/show?id=766713993a1' target=_blank style='color:#2F92EE;'>#Pediatric#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13993, encryptionId=766713993a1, topicName=Pediatric)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Thu Nov 19 08:47:00 CST 2015, time=2015-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725728, encodeId=433d1e2572863, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Thu Apr 16 12:47:00 CST 2015, time=2015-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1513606, encodeId=9b65151360683, content=<a href='/topic/show?id=7e1c23814ea' target=_blank style='color:#2F92EE;'>#乳酸杆菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23814, encryptionId=7e1c23814ea, topicName=乳酸杆菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=391710575663, createdName=陆成振, createdTime=Fri Jan 16 04:47:00 CST 2015, time=2015-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=14319, encodeId=629114319f0, content=吗咪爱有效的, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=223.104.5.**, createdTime=Wed Jan 14 15:48:00 CST 2015, time=2015-01-14, status=1, ipAttribution=)]
    2015-11-19 hbwxf

    #Pediatric#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1637022, encodeId=8bc7163e02276, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Jul 22 20:47:00 CST 2015, time=2015-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958403, encodeId=66741958403d9, content=<a href='/topic/show?id=766713993a1' target=_blank style='color:#2F92EE;'>#Pediatric#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13993, encryptionId=766713993a1, topicName=Pediatric)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Thu Nov 19 08:47:00 CST 2015, time=2015-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725728, encodeId=433d1e2572863, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Thu Apr 16 12:47:00 CST 2015, time=2015-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1513606, encodeId=9b65151360683, content=<a href='/topic/show?id=7e1c23814ea' target=_blank style='color:#2F92EE;'>#乳酸杆菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23814, encryptionId=7e1c23814ea, topicName=乳酸杆菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=391710575663, createdName=陆成振, createdTime=Fri Jan 16 04:47:00 CST 2015, time=2015-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=14319, encodeId=629114319f0, content=吗咪爱有效的, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=223.104.5.**, createdTime=Wed Jan 14 15:48:00 CST 2015, time=2015-01-14, status=1, ipAttribution=)]
    2015-04-16 feather89

    #PE#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1637022, encodeId=8bc7163e02276, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Jul 22 20:47:00 CST 2015, time=2015-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958403, encodeId=66741958403d9, content=<a href='/topic/show?id=766713993a1' target=_blank style='color:#2F92EE;'>#Pediatric#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13993, encryptionId=766713993a1, topicName=Pediatric)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Thu Nov 19 08:47:00 CST 2015, time=2015-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725728, encodeId=433d1e2572863, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Thu Apr 16 12:47:00 CST 2015, time=2015-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1513606, encodeId=9b65151360683, content=<a href='/topic/show?id=7e1c23814ea' target=_blank style='color:#2F92EE;'>#乳酸杆菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23814, encryptionId=7e1c23814ea, topicName=乳酸杆菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=391710575663, createdName=陆成振, createdTime=Fri Jan 16 04:47:00 CST 2015, time=2015-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=14319, encodeId=629114319f0, content=吗咪爱有效的, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=223.104.5.**, createdTime=Wed Jan 14 15:48:00 CST 2015, time=2015-01-14, status=1, ipAttribution=)]
    2015-01-16 陆成振

    #乳酸杆菌#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1637022, encodeId=8bc7163e02276, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Jul 22 20:47:00 CST 2015, time=2015-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958403, encodeId=66741958403d9, content=<a href='/topic/show?id=766713993a1' target=_blank style='color:#2F92EE;'>#Pediatric#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13993, encryptionId=766713993a1, topicName=Pediatric)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Thu Nov 19 08:47:00 CST 2015, time=2015-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725728, encodeId=433d1e2572863, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Thu Apr 16 12:47:00 CST 2015, time=2015-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1513606, encodeId=9b65151360683, content=<a href='/topic/show?id=7e1c23814ea' target=_blank style='color:#2F92EE;'>#乳酸杆菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23814, encryptionId=7e1c23814ea, topicName=乳酸杆菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=391710575663, createdName=陆成振, createdTime=Fri Jan 16 04:47:00 CST 2015, time=2015-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=14319, encodeId=629114319f0, content=吗咪爱有效的, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=223.104.5.**, createdTime=Wed Jan 14 15:48:00 CST 2015, time=2015-01-14, status=1, ipAttribution=)]
    2015-01-14 223.104.5.**

    吗咪爱有效的

    0