Expert Rev Vaccines:肺炎链球菌疫苗的应用研究

2017-04-23 MedSci MedSci原创

肺炎链球菌感染在临床上是十分常见的,这给患者及国家均带来了不小的负担。而肺炎链球菌疫苗的注射,能够有效的预防肺炎链球菌的感染。在Expert Rev Vaccines杂志中的一篇文章,对肺炎链球菌疫苗在不同经济水平的国家的有效性进行了研究。高收入国家(HICs)最先揭示了肺炎双球菌疫苗(PCVs)的高水平有效性。然而,肺炎球菌疾病(PD)在非高收入国家(NHICs)中的负担较高收入国家(HICs)

肺炎链球菌感染临床上是十分常见的,这给患者及国家均带来了不小的负担。而肺炎链球菌疫苗的注射,能够有效的预防肺炎链球菌的感染

在Expert Rev Vaccines杂志中的一篇文章,对肺炎链球菌疫苗在不同经济水平的国家的有效性进行了研究。高收入国家(HICs)最先揭示了肺炎双球菌疫苗(PCVs)的高水平有效性。然而,肺炎球菌疾病(PD)在非高收入国家(NHICs)中的负担较高收入国家(HICs)更严重,对后者进行疫苗的评估是至关重要的。

该研究者通过使用PubMed收索肺炎双球菌疫苗(PCVs)有效性的相关文献。一些研究结果对非高收入国家(NHICs)中肺炎双球菌疫苗(PCVs)有效性进行了描述。该研究对比了非高收入国家与高收入国家中,肺炎双球菌疫苗(PCVs)对侵袭性肺炎球菌疾病及肺炎发生率的影响。

研究者最终得出结论,肺炎双球菌疫苗(PCVs)在非高收入国家与高收入国家中使用均是有效的。肺炎链球菌疾病的总体发生率的下降与多数疫苗血清型的消失有关。侵袭性的肺炎球菌疾病主要见于未注射血清疫苗的人群。

因此该研究者得出结论,我们应该继续对侵袭性肺炎链球菌的多方面信息进行检测与管理

原始出处:

Cohen R, Cohen JF, Chalumeau M,et al.Impact of pneumococcal conjugate vaccines for children in high- and non-high-income countries.Expert Rev Vaccines. 2017 Apr 14. doi: 10.1080/14760584.2017.1320221.

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    2017-04-30 kalseyzl
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    2017-11-27 feather89
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