Radiology:术前磁共振成像鉴定侵袭性乳腺癌瘤周水肿的预后价值。

2018-04-06 shaosai MedSci原创

目的 探讨乳腺癌术前乳房磁共振(MR)成像对肿瘤复发患者肿瘤周围水肿的预后价值。

目的 探讨乳腺癌术前乳房磁共振(MR)成像对肿瘤复发患者肿瘤周围水肿的预后价值。

材料与方法 2011年1月至2012年12月,共有353名女性(平均年龄49岁,范围27-77岁)做过术前磁共振成像并进行了乳房切除术或保乳手术的浸润性乳腺癌女性患者。两名放射科医师根据T2加权像上肿瘤周围信号强度的程度独立评估瘤周水肿。采用多因素Cox比例风险模型,综合鉴别改善(IDI)和连续净分类改善(NRI)指标评估疾病复发与肿瘤周围水肿和临床病理特征之间的关系。

结果 中位随访27.2个月后,24名患者(6.8%)有疾病复发。多因素分析显示,N分期较高(危险比= 4.84,P = .002),淋巴管侵犯(危险比= 2.48,P = 0.044)和瘤周水肿(危险比= 2.77,P = 0.022)是疾病复发相关的独立因素。 IDI和持续的NRI显示当将瘤周水肿添加到确定的临床病理特征(IDI = 0.061,P <.001;连续NRI = 0.334,P = .012)时,其疾病复发诊断准确性显着提高。

结论 术前磁共振成像鉴定的瘤周水肿与疾病复发存在独立相关性。肿瘤周围水肿评估可能为浸润性乳腺癌患者提供更好的预后。

原始出处:


10.1148/radiol.2017171157

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    2018-04-24 wxl882001

    了解一下

    0

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    2018-04-20 1e145228m78(暂无匿称)

    学习了.谢谢作者分享!

    0

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    2018-04-08 sunyl07
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    2018-04-06 虈亣靌

    谢谢分享学习了

    0

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    2018-04-06 1ddf0692m34(暂无匿称)

    学习了.长知识

    0

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