Radiology:90Y放射学栓塞术治疗曾行胆管介入治疗的肝脏恶性肿瘤发生感染的风险因素有哪些?

2018-07-18 shaosai MedSci原创

本研究旨在验证对曾有胆管介入史的肝恶性肿瘤患者行钇90 (90Y)经动脉放射性栓塞术(TARE)后肝胆管感染的发生率,并将结果发表在radiology上。

本研究旨在验证对曾有胆管介入史的肝恶性肿瘤患者行90 (90Y)经动脉放射性栓塞术(TARE)后肝胆管感染的发生率,并将结果发表在radiology上。

本研究分析了有胆管介入史的肝恶性肿瘤且行TARE治疗的患者的病历。手机肝脏功能、90Y剂量、抗生素预防和胃肠道准备情况。主要结果为出现肝脏感染

结果为,共有126例有原发性(n = 39)或转移性(n = 87)肝恶性肿瘤且有胆管介入史的患者(男性84例,女性42例,平均年龄68.8岁)。肝脏感染(肝脏脓肿9例,胆管炎5例)共出现在10/126例患者中。所有患者均行住院治疗。10例患者需要穿刺脓肿引流,3例患者行内镜导管引流和取石术,1例患者需要穿刺胆管引流5例患者感染得到控制,4例患者死亡(2例患者死于感染,2例患者死于肿瘤进展),1例患者仍进行抗生素治疗。使用玻璃微球(P = .02)、肝脏切除或消融术史(P = .02)和年龄较小(P = .003)是发生感染风险较高的独立预测因子。

本研究表明,曾行胆管介入治疗的肝脏恶性肿瘤行TARE后发生的感染并发症(脓肿、胆管炎)虽然发生率较低,但是较为严重的并发症。

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    2018-07-20 kkunny
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    2018-07-18 liumin1987

    栓塞术治疗恶性肿瘤要注意预防感染并发症

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