JAHA:2型糖尿病患者肥胖与不良预后的相关性研究

2018-11-16 MedSci MedSci原创

近期研究显示糖尿病患者可能存在肥胖悖论现象。本研究的目的旨在评估2型糖尿病患者的不良预后事件与肥胖的关系。本研究纳入了ACCORD 临床研究中的有10年2型糖尿病史的患者。主要终点事件是全因死亡率,次要终点事件是心源性死亡、非致死性心梗和卒中。分析结果显示,三级肥胖患者(BMI≥40)的全因死亡率最高,二级肥胖其次,超重患者的风险最小。患者的BMI与腰围存在相关性(r=0.802),BMI与主要和

近期研究显示糖尿病患者可能存在肥胖悖论现象。本研究的目的旨在评估2型糖尿病患者的不良预后事件与肥胖的关系。

本研究纳入了ACCORD 临床研究中的有10年2型糖尿病史的患者。主要终点事件是全因死亡率,次要终点事件是心源性死亡、非致死性心梗和卒中。分析结果显示,三级肥胖患者(BMI≥40)的全因死亡率最高,二级肥胖其次,超重患者的风险最小。患者的BMI与腰围存在相关性(r=0.802),BMI与主要和次要重点事件的关系和腰围与主要和次要终点事件的关系类似(与全因死亡率呈J型相关,与次要终点事件呈V型相关)。

研究结果显示,在有10年2型糖尿病史的患者中不存在肥胖悖论,三级肥胖患者的全因死亡率最高。

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    2018-11-16 misszhang

    谢谢MedSci提供最新的资讯

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