BMC Anesthesiol:中枢或外周给予舒芬太尼会影响阿片类药物引起的咳嗽的发生

2018-07-30 MedSci MedSci原创

阿片类药物引起的咳嗽(OIC)是麻醉诱导期间阿片类药物使用最常见的并发症之一。本研究旨在评估不同静脉途径介导的OIC发生率。 选择全身麻醉下进行择期手术的102例(ASA I-II)患者,随机分为两组:中心静脉组(CV组,n = 51)和外周静脉组(PV组,n = 51)。评估诱导期间注射舒芬太尼后1分钟内 OIC的发生率,发作时间和严重程度。同时,还记录心率(HR)和血压(BP)以评估血液

阿片类药物引起的咳嗽(OIC)是麻醉诱导期间阿片类药物使用最常见的并发症之一。本研究旨在评估不同静脉途径介导的OIC发生率。

选择全身麻醉下进行择期手术的102例(ASA I-II)患者,随机分为两组:中心静脉组(CV组,n = 51)和外周静脉组(PV组,n = 51)。评估诱导期间注射舒芬太尼后1分钟内 OIC的发生率,发作时间和严重程度。同时,还记录心率(HR)和血压(BP)以评估血液动力学变化。

结果显示,CV组的OIC发生率为10/51(20.4%),PV组为16/51(32%),与外周静脉途径相比,接受中心静脉给药的患者,OIC的发生较少(P <0.05),且严重OIC的发生率明显降低(P <0.05)。此外,两组在OIC和血流动力学之间差异不明显(P> 0.05)。

综上所述,该研究研究表明,通过中心静脉途径给予舒芬太尼可降低OIC的发生率和严重程度,但血流动力学状态无明显变化。

原始出处:


He J, Zhu L, et al., Dose selection of central or peripheral administration of sufentanil affect opioid induced cough?: a prospective, randomized, controlled trial. BMC Anesthesiol. 2018 Apr 10;18(1):38. doi: 10.1186/s12871-018-0502-z.

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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Thu Aug 02 19:27:35 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335550, encodeId=112a3355500c, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Aug 01 14:15:45 CST 2018, time=2018-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335549, encodeId=3f2e33554923, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Aug 01 14:15:13 CST 2018, time=2018-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1253064, encodeId=a86212530644f, content=<a href='/topic/show?id=13159e8871d' target=_blank style='color:#2F92EE;'>#阿片类药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97887, encryptionId=13159e8871d, topicName=阿片类药物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c83329, createdName=10518093zz, createdTime=Wed Aug 01 08:03:00 CST 2018, time=2018-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1309102, encodeId=a37f130910203, content=<a href='/topic/show?id=a0179e879ac' target=_blank style='color:#2F92EE;'>#阿片类#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97879, encryptionId=a0179e879ac, topicName=阿片类)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7e12358, createdName=lhlxtx, createdTime=Wed Aug 01 08:03:00 CST 2018, time=2018-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1384820, encodeId=62d5138482046, content=<a href='/topic/show?id=93918690e81' target=_blank style='color:#2F92EE;'>#芬太尼#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86907, encryptionId=93918690e81, topicName=芬太尼)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d139492, createdName=xue8602, createdTime=Wed Aug 01 08:03:00 CST 2018, time=2018-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588335, encodeId=8bab158833552, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Wed Aug 01 08:03:00 CST 2018, time=2018-08-01, status=1, ipAttribution=)]
    2018-08-02 wxl882001

    了解一下

    0

  5. 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createdName=xue8602, createdTime=Wed Aug 01 08:03:00 CST 2018, time=2018-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588335, encodeId=8bab158833552, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Wed Aug 01 08:03:00 CST 2018, time=2018-08-01, status=1, ipAttribution=)]
    2018-08-01 131****1460

    学习了受益匪浅

    0

  6. 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createdName=xue8602, createdTime=Wed Aug 01 08:03:00 CST 2018, time=2018-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588335, encodeId=8bab158833552, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Wed Aug 01 08:03:00 CST 2018, time=2018-08-01, status=1, ipAttribution=)]
    2018-08-01 131****1460

    学习了受益匪浅

    0

  7. 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  8. 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    2018-08-01 lhlxtx
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    2018-08-01 xue8602
  10. 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createdName=xue8602, createdTime=Wed Aug 01 08:03:00 CST 2018, time=2018-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588335, encodeId=8bab158833552, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Wed Aug 01 08:03:00 CST 2018, time=2018-08-01, status=1, ipAttribution=)]
    2018-08-01 skhzy