Stroke:基底动脉斑块患者,斑块内出血与急性梗死的关系

2015-09-25 phylis 译 MedSci原创

背景和目的:高分辨磁共振(HRMRI)是检测病态动脉壁的理想方法,因为HRMRI是一种无创并且组织特征区分能力较高的一种检查方法。这篇研究旨在评估应用HRMRI检测基底动脉(BA)动脉粥样硬化患者的斑块内出血的发生情况及其临床相关性。 方法:研究人员分析了74名患者(45名有症状,29名无症状的患者)的HRMRI以及临床数据,所有受试者存在超过50%的BA狭窄。在磁化强度预备梯度回波序列(MPRA

背景和目的:高分辨磁共振(HRMRI)是检测病态动脉壁的理想方法,因为HRMRI是一种无创并且对组织特征区分能力较高的一种检查方法。这篇研究旨在评估应用HRMRI检测基底动脉(BA)动脉粥样硬化患者的斑块内出血的发生情况及其临床相关性。

方法:研究人员分析了74名患者(45名有症状,29名无症状的患者)的HRMRI以及临床数据,所有受试者存在超过50%的BA狭窄。在磁化强度预备梯度回波序列(MPRAGE)上,BA斑块高信号强度是相邻肌肉信号强度超过150%的区域。分析BA斑块区域存在IPH和临床表现的关系。

结果:HRMRI显示有30名患者存在IPH(42.3%,24个有症状,6个无症状)。MR阳性的IPH组的症状性损伤比MR阴性组患者更普遍(80% VS 48.8%)。并且,与低度狭窄组相比,高度狭窄组MR预测IPH的发生更普遍。与IPH患者MRRAGE阴性组相比,IPH患者MRRAGE阳性的患者发生急性局灶性卒中的RR值为1.64。

结论:HRMRI显示BA斑块区域存在IPH非常普遍,并与急性卒中相关。

原文出处:

Yu JH, Kwak HS, Chung GH,et al.Association of Intraplaque Hemorrhage and Acute Infarction in Patients With Basilar Artery Plaque. Stroke. 2015 Aug 25.


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Stroke:斑块内出血与基底动脉斑块患者的急性脑梗死的相关性

高分辨率磁共振成像(HRMRI)是病变动脉壁理想的序列检查方式,因为它是无创的,具有较好的鉴别组织特性能力。本研究的目的是评估基底动脉(BA)粥样硬化患者使用HRMRI检测斑块内出血(IPH)患病率和临床的相关性。研究人员分析了74例患者(45例有症状,29例无症状)的HRMRI和临床资料,所有这些患者都有>50%的BA狭窄。磁化准备快速采集梯度回波的一个BA斑块高信号强度被定义为与从相邻的