Electron Physician:吸烟对慢性牙周炎患者牙龈组织炎症细胞浸润亚型的影响

2017-10-11 MedSci MedSci原创

背景慢性牙周炎患者血液和龈沟液检测表明,吸烟会增加细胞因子的产生。目的评估吸烟和非吸烟受试者牙周炎和健康组织单核炎症细胞浸润免疫标记物的表达。方法该病例对照研究选取了2016年转诊到伊朗马什哈德牙科学院牙周病诊所的41名患者。参与者全部为伊朗Khorasanian人,年龄在35-65岁之间。通过常规牙周瓣手术获得牙龈活检。使用免疫组织化学进行CD20,CD3,CD68和CD45RO标记物检测。使用

背景


慢性牙周炎患者血液和龈沟液检测表明,吸烟会增加细胞因子的产生。

目的

评估吸烟和非吸烟受试者牙周炎和健康组织单核炎症细胞浸润免疫标记物的表达。

方法

该病例对照研究选取了2016年转诊到伊朗马什哈德牙科学院牙周病诊所的41名患者。参与者全部为伊朗Khorasanian人,年龄在35-65岁之间。通过常规牙周瓣手术获得牙龈活检。使用免疫组织化学进行CD20,CD3,CD68和CD45RO标记物检测。使用SPSS 15进行数据分析,采用单因素方差分析和Tukey HSD检验。

结果

与吸烟者相比,不吸烟受试者的健康和牙周炎组织活检显示CD20 +,CD68 +,CD3 +细胞明显较多(p <0.00),而CD45RO无显著性差异(p = 0.120)。

结论

吸烟导致牙周膜浸润性单核慢性炎症细胞减少。

原始出处:

Mehrdad Radvar, Hooman Shafaee, et al., The effect of smoking on inflammatory cell infiltrate subtypes in gingival tissue of patients with chronic periodontitis. Electron Physician. 2017 Aug; 9(8): 4961–4967. Published online 2017 Aug 25. doi:  10.19082/4961

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    不错的文章值得推荐

    0

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    2017-10-11 changjiu

    学习了.谢谢

    0

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