Stroke: 颈部动脉夹层患者磁共振成像与缺血性卒中相关临床因素分析

2018-10-21 MedSci MedSci原创

颈动脉夹层是年轻人缺血性卒中的主要原因,并会呈现各种影像学表现,包括狭窄和壁内血肿(IMH)。本项研究的目标是确定管腔表现和IMH对急性缺血性卒中的影响及严重T1加权序列是否能更可靠地诊断IMH。

背景和目的
颈动脉夹层是年轻人缺血性卒中的主要原因,并会呈现各种影像学表现,包括狭窄和壁内血肿(IMH)。本项研究的目标是确定管腔表现和IMH对急性缺血性卒中的影响及严重T1加权序列是否能更可靠地诊断IMH。

方法
这项研究为一项回顾性研究,研究人员对254名进行了磁共振成像/磁共振血管造影。成像包括标准涡轮自旋回波(TSE)T1-脂肪饱和度和重度T1加权流量抑制磁化 - 快速采集梯度 - 回忆序列。Kappa分析用于确定每个受试者4个血管中磁化准备的快速采集梯度回忆和T1-脂肪饱和度的IMH评估者间可靠性。

结果
本项研究中男性患者占了41.9%,平均年龄47.3±16.6岁。对于磁化准备的快速采集梯度回忆回波(κ= 0.83; 95%CI,0.78-0.86)与T1-脂肪饱和度(κ=0.58; 95%CI,0.57-0.68),IMH评估者间可靠性显着提高。最终急性卒中预测模型包括磁化准备快速采集梯度 - 回忆检测IMH(患病率,2.0; 95%CI,1.1-3.9;P= 0.034),狭窄,假性动脉瘤,男性,当前吸烟和非切除性卒中来源。与没有狭窄的模型(0.861; 95%CI,0.821-0.902),无狭窄和IMH相比,最终模型对急性卒中具有高度辨别力(AUC,0.902; 95%CI,0.872-0.932)。

结论
IMH可以用来检测疑似颈部动脉夹层患者的急性缺血性卒中的发生。此外,使用大量T1加权序列可以使IMH检测更可靠。

原始出处:

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    2019-07-14 howi
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    2018-10-23 衣带渐宽

    学习

    0

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    2018-10-21 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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阿替普酶静脉溶栓时发病4.5h内急性缺血性卒中的标准治疗方案。在14-27%的卒中患者中不知道发病时间,最常见的原因是醒后卒中。这些患者通常被排除在静脉溶栓治疗之外,仅部分患者适合机械性血栓切除术。

Radiology:动态增强乳腺MRI评估新辅助化疗后残余肿瘤大小

本项研究旨在探讨利用动态增强(DCE)乳腺MRI对新辅助化疗(NAC)后残留肿瘤大小的准确性。

JAMA Neurol:自发性脊髓损伤患者特征及诊断标准

研究基于确诊的自发性脊髓损伤患者特点,提出了自发性脊髓损伤临床、实验室以及MRI诊断标准,对临床实践及患者针对性治疗提供了依据