Epidemiol Rev:牙龈炎会增加全身癌症发病率

2017-04-29 MedSci MedSci原创

我们可能会从牙周疾病联想到口腔疾病或口腔癌,但是近期越来越多的人对牙周疾病的研究已经不仅仅是局限于口腔相关的范围了。牙周疾病可能会增加患者总体癌症发病率,这是事实吗?牙周疾病,包括牙龈炎和牙周炎,在成年人是非常常见的疾病,而且随着年龄的增加该疾病的严重程度递增。对于牙周疾病和口腔癌之间的关系,已经研究了几十年了;但越来越多的人对牙周疾病和整体癌症风险之间的联系感兴趣,将全身性炎症作为研究的焦点在生

我们可能会从牙周疾病联想到口腔疾病或口腔癌,但是近期越来越多的人对牙周疾病的研究已经不仅仅是局限于口腔相关的范围了。牙周疾病可能会增加患者总体癌症发病率,这是事实吗?

牙周疾病,包括牙龈炎和牙周炎,在成年人是非常常见的疾病,而且随着年龄的增加该疾病的严重程度递增。对于牙周疾病和口腔癌之间的关系,已经研究了几十年了;但越来越多的人对牙周疾病和整体癌症风险之间的联系感兴趣,将全身性炎症作为研究的焦点在生物学上是有道理的。

大量病例对照研究均着重的研究口腔健康在头部和颈部癌症中的作用。在过去的十年里有几个队列研究也对口腔健康与其他一些癌症的相关性进行了研究。现有数据提供支持积极的牙周疾病和口腔的风险之间的联系,肺癌胰腺癌;然而,额外需要前瞻性研究来更好的告知这些关联的强度,确定其他癌症与牙周疾病相关联。未来的研究应该包括足够大的样本量,提高牙周疾病的测量,全面调整吸烟和其他风险因素。

该文章提出,现有的证据表明牙周疾病与肺癌、胰腺癌、口腔癌症有着密切的联系。然而,目前还需更多的证据来表明其相关性的确切的,以及仍需更多的证据来证明牙周疾病与其他癌症之间有无关联。未来的研究应该包括足够大的样本量,改善牙周疾病的诊断方法,以及对吸烟和其他风险因素进行控制。

原始出处:

Michaud DS, Fu Z, Shi J,et al.Periodontal Disease, Tooth Loss, and Cancer Risk.Epidemiol Rev. 2017 Apr 25:1-10. doi: 10.1093/epirev/mxx006.

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  2. 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    2017-05-17 laymankey

    感谢分享一下!!

    0

  3. 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    2017-05-08 jyzxjiangqin

    牙龈炎增加全身癌症发病率。

    0

  4. 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authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sun Apr 30 07:56:22 CST 2017, time=2017-04-30, status=1, ipAttribution=)]
    2017-05-03 138****1711

    谢谢分享,学习了!

    0

  5. 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    2017-05-02 doctorJiangchao

    继续分享。

    0

  6. 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    2017-05-02 1771ae4158m

    学习一下很不错

    0

  7. 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    2017-05-01 虈亣靌

    学习一下觉得非常好

    0

  8. 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  9. 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    2017-04-30 doctorJiangchao

    好研究。

    0

  10. 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    2017-04-30 大爰

    好文章学习了!!

    0

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