J Rheumatol:纳入掌指关节对幼年特发性关节炎手腕MRI评分系统的影响

2018-08-25 xiangting MedSci原创

与原始评分相比,扩展评分的可靠性、结构有效性和对变化的敏感性更好。

这项研究通过纳入掌指关节(MCP),将磁共振成像(MRI)评分扩展用于幼年特发性关节炎(JIA)中手腕滑膜炎的评估,并比较了原始和扩展评分的度量特征。

70例JIA患者进行了手腕MRI检查,并由3名独立的阅片者根据(1)类风湿性关节炎MRI滑膜炎评分中的手腕部分(包括远端桡尺、桡腕、联合腕骨关节和腕掌关节);(2)包括MCP关节的扩展评分。38例患者进行了为期1年的MRI随访。计算两种评分的阅片者间一致性[组内相关系数(ICC),95%一致性界限(LOA)和加权Cohen'sκ]、与临床指标的相关性(Spearmanρ)、和对变化的敏感性[标准化反应均值(SRM)]。

原始评分的阅片者间一致性为中等(ICC 0.77; 95%CI 0.68-0.84),而扩展评分为良好(ICC 0.86; 95%CI 0.80-0.91)。使用95%LOA,相对较宽LOA的总评分变异性较差。各个关节的加权Cohen'sκ表明原始评分的一致性良好,而扩展评分的一致性为良好到优秀。扩展评分和反映疾病活动性临床指标的相关性更高。与原始评分相比,其SRM更高。

与原始评分相比,扩展评分的可靠性、结构有效性和对变化的敏感性更好。应考虑纳入MCP关节,以便更准确地评估JIA的疾病活动性和治疗效果。

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    2018-08-27 lmm397
  4. [GetPortalCommentsPageByObjectIdResponse(id=1975715, encodeId=841a19e571590, content=<a href='/topic/show?id=187f56605ae' target=_blank style='color:#2F92EE;'>#掌指关节#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56605, encryptionId=187f56605ae, topicName=掌指关节)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ea6321, createdName=okhuali, createdTime=Sun Jan 27 22:29:00 CST 2019, time=2019-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1894691, encodeId=3fe31894691ea, content=<a href='/topic/show?id=e45b6e859f3' target=_blank style='color:#2F92EE;'>#特发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67859, encryptionId=e45b6e859f3, topicName=特发性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=xinxin088, createdTime=Mon Oct 08 11:29:00 CST 2018, time=2018-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265782, encodeId=9b971265e8259, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Mon Aug 27 02:29:00 CST 2018, time=2018-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=340753, encodeId=9f28340e53f6, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Sat Aug 25 14:18:40 CST 2018, time=2018-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=340752, encodeId=fb98340e52cc, content=感谢小编为我们准备了如此丰盛的精神大餐,同时也向作者致谢!认真学习了,点赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30251637888, createdName=lietome15, createdTime=Sat Aug 25 13:17:05 CST 2018, time=2018-08-25, status=1, ipAttribution=)]
    2018-08-25 一个字-牛

    学习了谢谢分享

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1975715, encodeId=841a19e571590, content=<a href='/topic/show?id=187f56605ae' target=_blank style='color:#2F92EE;'>#掌指关节#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56605, encryptionId=187f56605ae, topicName=掌指关节)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ea6321, createdName=okhuali, createdTime=Sun Jan 27 22:29:00 CST 2019, time=2019-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1894691, encodeId=3fe31894691ea, content=<a href='/topic/show?id=e45b6e859f3' target=_blank style='color:#2F92EE;'>#特发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67859, encryptionId=e45b6e859f3, topicName=特发性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=xinxin088, createdTime=Mon Oct 08 11:29:00 CST 2018, time=2018-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265782, encodeId=9b971265e8259, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Mon Aug 27 02:29:00 CST 2018, time=2018-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=340753, encodeId=9f28340e53f6, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Sat Aug 25 14:18:40 CST 2018, time=2018-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=340752, encodeId=fb98340e52cc, content=感谢小编为我们准备了如此丰盛的精神大餐,同时也向作者致谢!认真学习了,点赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30251637888, createdName=lietome15, createdTime=Sat Aug 25 13:17:05 CST 2018, time=2018-08-25, status=1, ipAttribution=)]
    2018-08-25 lietome15

    感谢小编为我们准备了如此丰盛的精神大餐,同时也向作者致谢!认真学习了,点赞!

    0

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