中国介入心脏病学杂志:阜外医院乔树宾研究称,这个指标评估化学消融治疗肥厚型梗阻心肌病效果更好

2017-04-05 卢芳 中国循环杂志

阜外医院乔树宾、刘蓉等进行的研究发现,肥厚型梗阻性心肌病患者N末端B型利钠肽原(NT-proBNP)水平受心房大小及心室肥厚程度影响,且接受治疗前后NT-proBNP水平变化有一定规律,远期NT-proBNP水平显着下降。研究者认为,对于接受化学消融术的患者,随访时不仅需要复查超声心动图,了解心房、心室大小,室间隔及室壁厚度,流出道压差,还应该测定NT-proBNP水平,以协助评定手术效果及判断长

阜外医院乔树宾、刘蓉等进行的研究发现,肥厚型梗阻性心肌病患者N末端B型利钠肽原(NT-proBNP)水平受心房大小及心室肥厚程度影响,且接受治疗前后NT-proBNP水平变化有一定规律,远期NT-proBNP水平显着下降。

研究者认为,对于接受化学消融术的患者,随访时不仅需要复查超声心动图,了解心房、心室大小,室间隔及室壁厚度,流出道压差,还应该测定NT-proBNP水平,以协助评定手术效果及判断长期预后。

这项研究显示,在行化学消融术前,较高NT-proBNP水平患者左心房内径、最大左心室厚度、室间隔厚度、左心室后壁厚度均比较低水平者显着增高。不过,左心室流出道压差、左心室射血分数无显着差异。

在术后2天时,NT-proBNP升高,而术后1年时较术前显着下降。

该研究共纳入82例行化学消融肥厚型梗阻性心肌病患者,根据其NT-proBNP水平高低排列,前41例定为高NT-proBNP水平,平均值为(2184.91±967.09)fmol/ml;后41例定为低NT-proBNP水平,平均值为(771.18±215.85)fmol/ml。完成1年随访者有50例。

原始出处:

刘蓉,袁建松,胡奉环,等. 肥厚型梗阻性心肌病化学消融术后N 末端B 型利钠肽原水平的变化特点. 《中国介入心脏病学杂志》 2016年06期

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    2017-08-14 qblt
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    2017-04-06 laymankey

    感谢分享一下!

    0

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