Science:研究发现这种抗生素可以有效阻止癌细胞的扩散!

2017-11-25 佚名 medicalxpress

来自哈佛大学的研究人员在一项新的研究中发现证据表明,在结肠癌癌细胞向身体其他器官进行转移的时候,会携带某种细菌。研究结果发表在《科学》杂志上,该小组描述了他们对细菌及其与结肠癌病因可能的联系。

来自哈佛大学的研究人员在一项新的研究中发现证据表明,在结肠癌癌细胞向身体其他器官进行转移的时候,会携带某种细菌。研究结果发表在《科学》杂志上,该小组描述了他们对细菌及其与结肠癌病因可能的联系。

先前的研究表明,细菌与肿瘤细胞一起存在于各种类型的癌症中,这使得医学界的一些人怀疑它们是否是肿瘤形成的真正原因。名为具核梭杆菌的细菌已经被证实存在与结肠癌细胞中。在这项新的研究中,研究人员想知道当这些癌细胞已经转移到身体其他部位的时候,同样的细菌能否存在于结肠癌肿瘤细胞中。

为了找出答案,研究人员从结肠癌患者体内采集了组织样本。在研究过程中,他们发现,在许多情况下,同一细菌菌株存在于肿瘤中,即使结肠癌细胞已经发生转移,结肠癌最常见的转移位置就是肝脏,但没有证据表明结肠癌癌细胞中的细菌,存在于肝脏中。

研究人员对这一发现很感兴趣,研究人员将肿瘤植入健康的老鼠体内,这样他们发现那些有细菌的肿瘤开始生长了。接下来,研究小组测试了使用能够杀死F.具核梭杆菌的抗生素来治疗结肠癌小鼠的可能性。他们发现这样做确实减缓了肿瘤的生长。

这一发现使研究人员找到了对抗结肠癌的新方向,希望进一步的研究可以证明此法的有效性和安全性。

原始出处:

Susan Bullman, Chandra S. Pedamallu,Ewa Sicinska1, et.al. Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer. Science

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    2017-11-27 yxch36
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    2017-11-27 jichang
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    2017-11-26 三生有幸9135

    学习一下谢谢分享

    0

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    2017-11-25 lucycici

    学习了

    0

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