J Periodontal Implant Sci:唾液aMMP-8与牙周风险评估参数之间的关联

2018-10-15 MedSci MedSci原创

这项回顾性横断面研究旨在评估唾液中活性基质金属蛋白酶8(aMMP-8)椅旁(POC)测试的是否与接受支持性牙周治疗(SPT)的患者的牙周风险评估参数相关。 研究共纳入125名接受常规SPT的患者。入选标准:慢性牙周炎,至少1次非手术牙周治疗(洁治和根面平整),遵循常规SPT(每年至少一次),至少6个剩余牙齿,获得临床和aMMP-8的检查结果。除了系统性因素(如吸烟和糖尿病),收集口腔卫生指数

这项回顾性横断面研究旨在评估唾液中活性基质金属蛋白酶8(aMMP-8)椅旁(POC)测试的是否与接受支持性牙周治疗(SPT)的患者的牙周风险评估参数相关。

研究共纳入125名接受常规SPT的患者。入选标准:慢性牙周炎,至少1次非手术牙周治疗(洁治和根面平整),遵循常规SPT(每年至少一次),至少6个剩余牙齿,获得临床和aMMP-8的检查结果。除了系统性因素(如吸烟和糖尿病),收集口腔卫生指数(改良龈沟出血指数[mSBI]和近似斑块指数),探诊深度,探诊出血,牙齿情况(龋坏,缺失和充填牙齿)。使用商业POC测试系统(Periomarker,Hager&Werken,Duisburg,Germany)测试唾液aMMP-8水平。如果合适,使用t检验,Mann-Whitney U检验,Fisher精确检验和χ2检验进行统计学分析(P <0.05)。

结果显示,只有mSBI与阳性唾液aMMP-8发现明显相关(aMMP-8阳性 VS. 阴性:27.8%±20.9% VS. 18.0%±14.5%; P = 0.017)。aMMP-8与吸烟、糖尿病、牙周参数或与维持间隔相关的参数之间未发现明显的相关性(P> 0.05)。

综上所述,该研究结果表明,唾液aMMP-8椅旁检查结果与接受SPT的患者牙周风险评估的常用参数无关。POC唾液aMMP-8检测在SPT期间的风险评估和维持间隔调整中的诊断益处仍不清楚。

原始出处:

Gerhard Schmalz, Max Kristian Kummer, et al., Association of chairside salivary aMMP-8 findings with periodontal risk assessment parameters in patients receiving supportive periodontal therapy. J Periodontal Implant Sci. 2018 Aug; 48(4): 251–260.

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    2018-11-09 xuyong536
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    2019-01-30 feather89
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    2019-06-18 xuyu
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