Am J Obstet Gynecol:卵巢囊肿剔除术中双极电凝止血影响卵巢储备

2015-11-25 candy 译 MedSci原创

目的:本研究的目的为系统评价双极电凝卵巢囊肿剔除术对卵巢储备的影响。方法:我们检索了MEDLINE(1966-2015)、Scopus (2004-2015) 、ClinicalTrials.gov (2008-2015)、Cochrane Central Register (CENTRAL)这些数据库,以及电子检索研究的参考书目。在接受良性卵巢囊肿切除术后,跟踪随访,分别记录术后1、3、6和12

目的:本研究的目的为系统评价卵巢囊肿剔除术中双极电凝止血对卵巢储备的影响。

方法:我们检索了MEDLINE(1966-2015)、Scopus (2004-2015) 、ClinicalTrials.gov (2008-2015)、Cochrane Central Register (CENTRAL)这些数据库,以及电子检索研究的参考书目。在接受良性卵巢囊肿切除术后,跟踪随访,分别记录术后1、3、6和12个月患者的抗缪勒管激素水平(AMH)和窦卵泡计数(AFC),作为主要结果。

结果:最终,研究者将8项研究纳入到本次系统回顾中,共计545例女性患者。由于这些纳入的研究在方法学特征上有显著异质性,所以排除了荟萃分析。对纳入的这些研究数据进行分析,发现在卵巢囊肿切除术中使用双极电凝技术较卵巢缝合技术会显著降低术后头3个月的AMH和AFC。两项研究报道称这种影响会一直持续到术后6-12个月。

结论:AMH和AFC的低水平数据似乎可以说明:双极电凝其实会伴随对卵巢储备的损害。然而,由于纳入研究的异质性和潜在的偏倚,最终结果被排除。

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    2016-01-30 yhy100200
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    2016-06-20 yuandd
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    2015-11-27 jeanqiuqiu
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