Clin Gastroenterology H:术前内镜逆行胰胆管造影术与胰腺癌死亡率增加无关

2019-07-14 不详 MedSci原创

有研究报道,胰腺癌术前内镜逆行胰胆管造影术(ERCP)与术后感染并发症有关。关于术前ERCP对胰腺癌患者生存的影响知之甚少。本项研究旨在探究术前ERCP是否影响胰腺癌患者总体生存。

背景与目的
有研究报道,胰腺癌术前内镜逆行胰胆管造影术(ERCP)与术后感染并发症有关。关于术前ERCP对胰腺癌患者生存的影响知之甚少。本项研究旨在探究术前ERCP是否影响胰腺癌患者总体生存。

方法
研究人员对2000年到2011年间定位于胰头部癌症的65岁以上患者进行回顾性分析,使用反向倾向加权Cox比例风险模型评估ERCP对接受胰腺癌手术的患者生存的影响。

结果
在16670名胰头癌患者中,2890名(17.3%)接受了手术切除; 1864例(64.5%)患者接受术前ERCP。在调整了混杂因素之后,研究人员发现接受术前ERCP的患者与单独接受切除的患者相比,死亡风险没有增加(风险比,1.02; 95%CI,0.96-1.08)。

结论
与直接接受手术的患者相比,手术前接受ERCP治疗的胰腺癌患者死亡风险并未增加。

原始出处:

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CST 2019, time=2019-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1504736, encodeId=71641504e3632, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Tue Jul 16 10:08:00 CST 2019, time=2019-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1628387, encodeId=d99f162838e40, content=<a href='/topic/show?id=9a4e83503e4' target=_blank style='color:#2F92EE;'>#胆管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83503, encryptionId=9a4e83503e4, topicName=胆管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c21721182790, createdName=cmj15wellington, createdTime=Tue Jul 16 10:08:00 CST 2019, time=2019-07-16, status=1, ipAttribution=)]
    2019-10-30 许安
  5. 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  6. 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  7. 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CST 2019, time=2019-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1504736, encodeId=71641504e3632, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Tue Jul 16 10:08:00 CST 2019, time=2019-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1628387, encodeId=d99f162838e40, content=<a href='/topic/show?id=9a4e83503e4' target=_blank style='color:#2F92EE;'>#胆管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83503, encryptionId=9a4e83503e4, topicName=胆管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c21721182790, createdName=cmj15wellington, createdTime=Tue Jul 16 10:08:00 CST 2019, time=2019-07-16, status=1, ipAttribution=)]
    2019-07-16 sodoo
  8. 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