Gastroenterology:缺铁性贫血患者乳糜泻风险增加

2018-04-23 zhangfan MedSci原创

研究证实每31名缺铁性贫血患者中就有1名为乳糜泻患者,该流行病学研究证实了现行指南的正确性

乳糜泻患者的贫血发病率较高,现行指南建议缺铁性贫血患者接受乳糜泻筛查,但真实世界中,贫血患者中乳糜泻的发病率尚不清楚。近日研究人员就缺铁性贫血(IDA)患者中乳糜泻的发病率进行了系统研究。

研究人员收集了截止2017年7月,乳糜泻合并贫血以及缺铁性贫血患者的相关研究资料,通过固定效应逆方差加权模型考察乳糜泻发病率,通过荟萃回归评价亚组间异质性。

本研究总计收录了18个相关研究,总计2998名患者,患者来自英国、美国、意大利、土耳其、伊朗以及以色列。未加权乳糜泻患病率为4.8%(n=143)。加权集合分析后,IDA患者中乳糜泻的发病率为3.2%(95% CI, 2.6%-3.9%),但异质性较高(I2 = 67.7%)。年龄以及性别对IDA患者乳糜泻发病率影响不显著。多因素分析显示,女性、年龄以及一般人群中乳糜泻的发病率与IDA患者乳糜泻发病率无关。在高质量的8项研究中,乳糜泻合并IDA的患病率为5.5% (95% CI, 4.1%-6.9%)。

研究证实每31名缺铁性贫血患者中就有1名为乳糜泻患者,该流行病学研究证实了现行指南的正确性。

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    2019-02-11 许安
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createdName=chaojitidian, createdTime=Wed Apr 25 00:56:00 CST 2018, time=2018-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308796, encodeId=a527308e96ce, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Tue Apr 24 09:10:08 CST 2018, time=2018-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308766, encodeId=3222308e6623, content=好文献.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Tue Apr 24 07:46:39 CST 2018, time=2018-04-24, status=1, ipAttribution=)]
    2018-04-26 1209e435m98(暂无昵称)

    学习了.谢谢分享

    0

  5. 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createdTime=Tue Apr 24 07:46:39 CST 2018, time=2018-04-24, status=1, ipAttribution=)]
    2018-04-25 yfjms

    学习

    0

  6. 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createdTime=Tue Apr 24 07:46:39 CST 2018, time=2018-04-24, status=1, ipAttribution=)]
    2018-04-25 121832a9m88暂无昵称

    学习了

    0

  7. 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createdTime=Tue Apr 24 07:46:39 CST 2018, time=2018-04-24, status=1, ipAttribution=)]
  8. 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createdName=chaojitidian, createdTime=Wed Apr 25 00:56:00 CST 2018, time=2018-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308796, encodeId=a527308e96ce, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Tue Apr 24 09:10:08 CST 2018, time=2018-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308766, encodeId=3222308e6623, content=好文献.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Tue Apr 24 07:46:39 CST 2018, time=2018-04-24, status=1, ipAttribution=)]
  9. 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createdName=chaojitidian, createdTime=Wed Apr 25 00:56:00 CST 2018, time=2018-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308796, encodeId=a527308e96ce, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Tue Apr 24 09:10:08 CST 2018, time=2018-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308766, encodeId=3222308e6623, content=好文献.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Tue Apr 24 07:46:39 CST 2018, time=2018-04-24, status=1, ipAttribution=)]
    2018-04-24 龙胆草

    学习谢谢分享

    0

  10. 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createdTime=Tue Apr 24 07:46:39 CST 2018, time=2018-04-24, status=1, ipAttribution=)]
    2018-04-24 张新亮1853311252142e2fm

    好文献.学习了

    0

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