ESC2018丨抬头纹多也有问题,心血管死亡风险增加9倍

2018-08-27 卢芳 中国循环杂志

谢顶、耳垂折痕、皮肤下黄斑,都是一个人心血管病风险高的标志,不曾想皱纹居然也是长给心脏科医生看的。

谢顶、耳垂折痕、皮肤下黄斑,都是一个人血管病风险高的标志,不曾想皱纹居然也是长给心脏科医生看的。

在ESC2018上报道的一项对3200位受试者追踪了20年的研究发现,抬头纹若越多且深,血管死亡风险就越高。

研究显示,抬头纹多且深的人心血管死亡风险,是没有抬头纹者的10倍;抬头纹少的人其心血管死亡风险也要比没有抬头纹的人高。

这也是研究者在考虑了年龄、性别、受教育程度、吸烟否、血压、心率、有无糖尿病以及血脂水平等因素后的分析结果。

“不管是高胆固醇还是高血压,都得量吧。而我们这项研究结果简单直观,看一下患者的脸,就明白可能心血管已发出警报,需要给患者降降风险了。”研究者说。

为什么是皱纹?为什么是抬头纹,不是鱼尾纹?

首先,一个人脸部皱褶的形成,不仅是岁月的作用,而且还是喜怒哀乐等造成的面部运动的结果。

其次,胶原蛋白和氧化应激均在动脉粥样硬化和皱纹形成中扮有一定角色,而前额血管细小,可能对粥样斑块的堆积更为敏感,也就是说抬头纹或是血管老化的早期迹象之一。

就鱼尾纹而言,之前研究未发现其与心血管病风险相关。

研究者指出,这项研究首次发现了心血管风险和抬头纹的关系,今后还需进一步进行证实,当前如果门诊时,可以考虑用一用。因为这无需成本,也没有风险。

这项研究中,3200位受试者最初参加试验时均健康又强壮,年龄分别在32岁、42岁、52岁和62岁。研究者就此对其有无抬头纹,抬头纹多不多、深不深进行评分;其中没有抬头纹评为0分,略有纹路为1分,多而深则是3分。

其中15.2%的人得分2~3分,6.6%的人得分为1分,2.1%无抬头纹为0分。随访20年间,233人死亡。

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    2019-07-30 neurowu
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1785787, encodeId=e8041e85787a9, content=<a href='/topic/show?id=1cb16995e7' target=_blank style='color:#2F92EE;'>#ESC2018#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6995, encryptionId=1cb16995e7, topicName=ESC2018)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Tue Jul 30 23:45:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255792, encodeId=173a1255e929b, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Wed Aug 29 10:45:00 CST 2018, time=2018-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554195, encodeId=35fd155419514, content=<a href='/topic/show?id=ab025182080' target=_blank style='color:#2F92EE;'>#心血管死亡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51820, encryptionId=ab025182080, topicName=心血管死亡)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0fb814514579, createdName=huperzia, createdTime=Wed Aug 29 10:45:00 CST 2018, time=2018-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629869, encodeId=8bc7162986906, content=<a href='/topic/show?id=a913518225e' target=_blank style='color:#2F92EE;'>#心血管死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51822, encryptionId=a913518225e, topicName=心血管死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e76421361831, createdName=baoya, createdTime=Wed Aug 29 10:45:00 CST 2018, time=2018-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341567, encodeId=bca034156e39, content=没有参考的原文信息啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0f9a1659232, createdName=cheer50230, createdTime=Wed Aug 29 07:18:07 CST 2018, time=2018-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341566, encodeId=161034156618, content=没有原文啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0f9a1659232, createdName=cheer50230, createdTime=Wed Aug 29 07:17:37 CST 2018, time=2018-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341343, encodeId=69f5341343a9, content=学习,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Mon Aug 27 20:56:27 CST 2018, time=2018-08-27, status=1, ipAttribution=)]
    2018-08-29 cheer50230

    没有参考的原文信息啊

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1785787, encodeId=e8041e85787a9, content=<a href='/topic/show?id=1cb16995e7' target=_blank style='color:#2F92EE;'>#ESC2018#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6995, encryptionId=1cb16995e7, topicName=ESC2018)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Tue Jul 30 23:45:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255792, encodeId=173a1255e929b, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Wed Aug 29 10:45:00 CST 2018, time=2018-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554195, encodeId=35fd155419514, content=<a href='/topic/show?id=ab025182080' target=_blank style='color:#2F92EE;'>#心血管死亡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51820, encryptionId=ab025182080, topicName=心血管死亡)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0fb814514579, createdName=huperzia, createdTime=Wed Aug 29 10:45:00 CST 2018, time=2018-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629869, encodeId=8bc7162986906, content=<a href='/topic/show?id=a913518225e' target=_blank style='color:#2F92EE;'>#心血管死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51822, encryptionId=a913518225e, topicName=心血管死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e76421361831, createdName=baoya, createdTime=Wed Aug 29 10:45:00 CST 2018, time=2018-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341567, encodeId=bca034156e39, content=没有参考的原文信息啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0f9a1659232, createdName=cheer50230, createdTime=Wed Aug 29 07:18:07 CST 2018, time=2018-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341566, encodeId=161034156618, content=没有原文啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0f9a1659232, createdName=cheer50230, createdTime=Wed Aug 29 07:17:37 CST 2018, time=2018-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341343, encodeId=69f5341343a9, content=学习,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Mon Aug 27 20:56:27 CST 2018, time=2018-08-27, status=1, ipAttribution=)]
    2018-08-29 cheer50230

    没有原文啊

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1785787, encodeId=e8041e85787a9, content=<a href='/topic/show?id=1cb16995e7' target=_blank style='color:#2F92EE;'>#ESC2018#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6995, encryptionId=1cb16995e7, topicName=ESC2018)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Tue Jul 30 23:45:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255792, encodeId=173a1255e929b, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Wed Aug 29 10:45:00 CST 2018, time=2018-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554195, encodeId=35fd155419514, content=<a href='/topic/show?id=ab025182080' target=_blank style='color:#2F92EE;'>#心血管死亡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51820, encryptionId=ab025182080, topicName=心血管死亡)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0fb814514579, createdName=huperzia, createdTime=Wed Aug 29 10:45:00 CST 2018, time=2018-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629869, encodeId=8bc7162986906, content=<a href='/topic/show?id=a913518225e' target=_blank style='color:#2F92EE;'>#心血管死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51822, encryptionId=a913518225e, topicName=心血管死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e76421361831, createdName=baoya, createdTime=Wed Aug 29 10:45:00 CST 2018, time=2018-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341567, encodeId=bca034156e39, content=没有参考的原文信息啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0f9a1659232, createdName=cheer50230, createdTime=Wed Aug 29 07:18:07 CST 2018, time=2018-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341566, encodeId=161034156618, content=没有原文啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0f9a1659232, createdName=cheer50230, createdTime=Wed Aug 29 07:17:37 CST 2018, time=2018-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341343, encodeId=69f5341343a9, content=学习,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Mon Aug 27 20:56:27 CST 2018, time=2018-08-27, status=1, ipAttribution=)]
    2018-08-27 惠映实验室

    学习,谢谢分享。

    0