J Dent Res:第三磨牙拔除后的系统性炎症:一项病例对照研究

2017-08-09 MedSci MedSci原创

第三磨牙拔除是牙科中最常见的治疗之一。然而,有少量证据显示,有阻生或不完全阻生第三磨牙的个人存在宿主反应,并且这种宿主反应对手术拔除可能会有一定的影响。

第三磨牙拔除是牙科中最常见的治疗之一。然而,有少量证据显示,有阻生或不完全阻生第三磨牙的个人存在宿主反应,并且这种宿主反应对手术拔除可能会有一定的影响。

此项病例对照研究包含40名患者,评估以下内容:1) 系统性炎症、血管功能和新陈代谢(高敏感度C反应蛋白、脂类、纤维蛋白原、氧化性应激和内皮功能分析)的生物标记差异和2) 手术拔除对有双向阻生或不完全阻生第三磨牙患者的急性和短期影响,并与没有第三磨牙的对照个体相比较。

结果显示,经历第三磨牙拔除的患者比对照个体表现出更高水平的系统性炎症、氧化性应激和甘油三酯。值得注意的是,拔牙术后一周白血细胞计数上升,并且C反应蛋白和纤维蛋白原血清水平达到顶峰。拔牙后3个月,所有标记物水平回归基准值。另外,氧化性应激指示剂-丙二醛在第三磨牙拔除后水平显著下降。

结论:不完全阻生和阻生第三磨牙与较高的系统性炎症关系密切,并且牙齿拔除可以作为研究人类急性炎症的有效模型,也可以有益于全身效应。

原始出处

Graziani F, D'Aiuto F, et al. Systemic Inflammation after Third Molar Removal: A Case-Control Study. J Dent Res. 2017 Jul 1:22034517722775. doi: 10.1177/0022034517722775.

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    2018-03-22 xugc
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    2018-02-28 amyloid
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  7. [GetPortalCommentsPageByObjectIdResponse(id=1651366, encodeId=854e165136650, content=<a href='/topic/show?id=0e39e5792aa' target=_blank style='color:#2F92EE;'>#第三磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75792, encryptionId=0e39e5792aa, topicName=第三磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c6124182829, createdName=zexyw09, createdTime=Sat Oct 28 05:36:00 CST 2017, time=2017-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1984128, encodeId=a4281984128e6, content=<a href='/topic/show?id=77dee0776b6' target=_blank style='color:#2F92EE;'>#病例对照研究#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70776, encryptionId=77dee0776b6, topicName=病例对照研究)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a35a460, createdName=fengyi812, createdTime=Fri Jun 15 08:36:00 CST 2018, time=2018-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2016989, encodeId=2a0c2016989c8, content=<a href='/topic/show?id=9760e69058c' target=_blank style='color:#2F92EE;'>#系统性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76905, encryptionId=9760e69058c, topicName=系统性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2b9b368, createdName=qingrejiedu, createdTime=Fri Apr 20 02:36:00 CST 2018, time=2018-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1756158, encodeId=de631e5615813, content=<a href='/topic/show?id=cc81e0775ab' target=_blank style='color:#2F92EE;'>#病例对照#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70775, encryptionId=cc81e0775ab, topicName=病例对照)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=064637073830, createdName=xugc, createdTime=Thu Mar 22 14:36:00 CST 2018, time=2018-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1775330, encodeId=8b3c1e7533059, content=<a href='/topic/show?id=937d46650bf' target=_blank style='color:#2F92EE;'>#对照#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46650, encryptionId=937d46650bf, topicName=对照)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8ae138776909, createdName=amyloid, createdTime=Wed Feb 28 16:36:00 CST 2018, time=2018-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576136, encodeId=1d2e15e6136e3, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=570716304996, createdName=12498474m35暂无昵称, createdTime=Fri Aug 11 04:36:00 CST 2017, time=2017-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=231840, encodeId=4c0a23184051, content=学习了,谢谢。, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Wed Aug 09 13:59:30 CST 2017, time=2017-08-09, status=1, ipAttribution=)]
    2017-08-09 惠映实验室

    学习了,谢谢。

    0