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3D生物打印取得里程碑式进展：FDA授予AuriNovo孤儿药物认定用于小耳畸形患者的耳部重建

2019-11-21 Allan MedSci原创

小耳畸形AuriNovo3D生物打印
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3DBio Therapeutics是人类治疗用3D生物打印领域的新兴领导者，近日宣布，FDA授予AuriNovo孤儿药物认定，这是一种用于小耳畸形患者的耳部重建的研究性组合产品。

3DBio Therapeutics是人类治疗用3D生物打印领域的新兴领导者，近日宣布，FDA授予AuriNovo孤儿药物认定，这是一种用于小耳畸形患者的耳部重建的研究性组合产品。小耳畸形是一种罕见的先天性疾病，导致外耳（耳廓）比正常耳朵小，且畸形，有时在出生时就消失了。大多数情况下只影响一只耳朵。AuriNovo™将患者自身的耳软骨细胞整合到3D生物打印机中，产生全尺寸的耳朵结构，然后将AuriNovo™植入患者头部耳廓区域。

3DBio Therapeutics首席执行官丹尼尔·科恩（Daniel Cohen）博士说：“我们很高兴AuriNovo™获得孤儿药认定，这一里程碑强化了我们将AuriNovo™引入市场的承诺”。


原始出处：

https://www.firstwordpharma.com/node/1682491

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    2020-03-03 ms4964546379600229

    #小耳畸形#

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    2020-03-22 wwzzly

    #3D生物打印#

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    2020-10-27 ms6980045490879608

    #孤儿药物#

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topicList=[TopicDto(id=1246, encryptionId=5543124679, topicName=3D生物打印)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b96f328, createdName=wwzzly, createdTime=Sun Mar 22 11:09:00 CST 2020, time=2020-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1740116, encodeId=41a51e40116e4, content=<a href='/topic/show?id=f5a445431df' target=_blank style='color:#2F92EE;'>#孤儿药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45431, encryptionId=f5a445431df, topicName=孤儿药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a4f034650217, createdName=ms6980045490879608, createdTime=Tue Oct 27 05:09:00 CST 2020, time=2020-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2059317, encodeId=781c205931e9b, content=<a href='/topic/show?id=9fbe95e0015' target=_blank style='color:#2F92EE;'>#里程碑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95700, encryptionId=9fbe95e0015, topicName=里程碑)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2317301, createdName=xzw113, createdTime=Mon Jan 27 07:09:00 CST 2020, time=2020-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1336142, encodeId=eb4b133614258, content=<a href='/topic/show?id=792612047e' target=_blank style='color:#2F92EE;'>#3D#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1204, encryptionId=792612047e, topicName=3D)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/pSGl6CJeZ2PzWxdhCtrvv4U9Q281RV8e0AKmlB5ib93DibbiaRyOzmkCdz5F04cbfX5RGOpG4dOXvuQW1fumibVeBg/132, createdBy=fc342500110, createdName=ms9833124466084992, createdTime=Sat Nov 23 02:09:00 CST 2019, time=2019-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1362311, encodeId=6242136231118, content=<a href='/topic/show?id=9857e03444b' target=_blank style='color:#2F92EE;'>#畸形#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70344, encryptionId=9857e03444b, topicName=畸形)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca20190, createdName=wushaoling, createdTime=Sat Nov 23 02:09:00 CST 2019, time=2019-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1615968, encodeId=f2a21615968f7, content=<a href='/topic/show?id=519345433ea' target=_blank style='color:#2F92EE;'>#孤儿药物认定#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45433, encryptionId=519345433ea, topicName=孤儿药物认定)], attachment=null, 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time=2019-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375637, encodeId=6c6f3e56373e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/08/03/0e492dda8bcc1f98474b74c2863aca87.jpg, createdBy=068d2446376, createdName=Dr Z, createdTime=Fri Nov 22 07:07:55 CST 2019, time=2019-11-22, status=1, ipAttribution=)]
    2020-01-27 xzw113

    #里程碑#

    0

  5. 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23 02:09:00 CST 2019, time=2019-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1362311, encodeId=6242136231118, content=<a href='/topic/show?id=9857e03444b' target=_blank style='color:#2F92EE;'>#畸形#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70344, encryptionId=9857e03444b, topicName=畸形)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca20190, createdName=wushaoling, createdTime=Sat Nov 23 02:09:00 CST 2019, time=2019-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1615968, encodeId=f2a21615968f7, content=<a href='/topic/show?id=519345433ea' target=_blank style='color:#2F92EE;'>#孤儿药物认定#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45433, encryptionId=519345433ea, topicName=孤儿药物认定)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8cfd19711155, createdName=若水129, createdTime=Sat Nov 23 02:09:00 CST 2019, time=2019-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375644, encodeId=3c813e5644b8, content=当年上海交大曹谊林教授在老鼠背上长出人耳朵，原理相似，可惜后来似乎没有往药方面发展, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Fri Nov 22 09:24:30 CST 2019, time=2019-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375638, encodeId=04a83e563886, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bbc11488193, createdName=thm112988, createdTime=Fri Nov 22 07:09:12 CST 2019, time=2019-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375637, encodeId=6c6f3e56373e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/08/03/0e492dda8bcc1f98474b74c2863aca87.jpg, createdBy=068d2446376, createdName=Dr Z, createdTime=Fri Nov 22 07:07:55 CST 2019, time=2019-11-22, status=1, ipAttribution=)]
    2019-11-23 ms9833124466084992

    #3D#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2006286, encodeId=c8a62006286ed, content=<a href='/topic/show?id=58974e0973e' target=_blank style='color:#2F92EE;'>#小耳畸形#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47097, encryptionId=58974e0973e, topicName=小耳畸形)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Tue Mar 03 04:09:00 CST 2020, time=2020-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1981731, encodeId=ba501981e31e7, content=<a href='/topic/show?id=5543124679' target=_blank style='color:#2F92EE;'>#3D生物打印#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95700, encryptionId=9fbe95e0015, topicName=里程碑)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2317301, createdName=xzw113, createdTime=Mon Jan 27 07:09:00 CST 2020, time=2020-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1336142, encodeId=eb4b133614258, content=<a href='/topic/show?id=792612047e' target=_blank style='color:#2F92EE;'>#3D#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1204, encryptionId=792612047e, topicName=3D)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/pSGl6CJeZ2PzWxdhCtrvv4U9Q281RV8e0AKmlB5ib93DibbiaRyOzmkCdz5F04cbfX5RGOpG4dOXvuQW1fumibVeBg/132, createdBy=fc342500110, createdName=ms9833124466084992, createdTime=Sat Nov 23 02:09:00 CST 2019, time=2019-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1362311, encodeId=6242136231118, content=<a href='/topic/show?id=9857e03444b' target=_blank style='color:#2F92EE;'>#畸形#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70344, encryptionId=9857e03444b, topicName=畸形)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca20190, createdName=wushaoling, createdTime=Sat Nov 23 02:09:00 CST 2019, time=2019-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1615968, encodeId=f2a21615968f7, content=<a href='/topic/show?id=519345433ea' target=_blank style='color:#2F92EE;'>#孤儿药物认定#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45433, encryptionId=519345433ea, topicName=孤儿药物认定)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8cfd19711155, createdName=若水129, createdTime=Sat Nov 23 02:09:00 CST 2019, time=2019-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375644, encodeId=3c813e5644b8, content=当年上海交大曹谊林教授在老鼠背上长出人耳朵，原理相似，可惜后来似乎没有往药方面发展, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Fri Nov 22 09:24:30 CST 2019, time=2019-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375638, encodeId=04a83e563886, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bbc11488193, createdName=thm112988, createdTime=Fri Nov 22 07:09:12 CST 2019, time=2019-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375637, encodeId=6c6f3e56373e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/08/03/0e492dda8bcc1f98474b74c2863aca87.jpg, createdBy=068d2446376, createdName=Dr Z, createdTime=Fri Nov 22 07:07:55 CST 2019, time=2019-11-22, status=1, ipAttribution=)]
    2019-11-23 wushaoling

    #畸形#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2006286, encodeId=c8a62006286ed, content=<a href='/topic/show?id=58974e0973e' target=_blank style='color:#2F92EE;'>#小耳畸形#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47097, encryptionId=58974e0973e, topicName=小耳畸形)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Tue Mar 03 04:09:00 CST 2020, time=2020-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1981731, encodeId=ba501981e31e7, content=<a href='/topic/show?id=5543124679' target=_blank style='color:#2F92EE;'>#3D生物打印#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, 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23 02:09:00 CST 2019, time=2019-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1362311, encodeId=6242136231118, content=<a href='/topic/show?id=9857e03444b' target=_blank style='color:#2F92EE;'>#畸形#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70344, encryptionId=9857e03444b, topicName=畸形)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca20190, createdName=wushaoling, createdTime=Sat Nov 23 02:09:00 CST 2019, time=2019-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1615968, encodeId=f2a21615968f7, content=<a href='/topic/show?id=519345433ea' target=_blank style='color:#2F92EE;'>#孤儿药物认定#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45433, encryptionId=519345433ea, topicName=孤儿药物认定)], attachment=null, 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time=2019-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375637, encodeId=6c6f3e56373e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/08/03/0e492dda8bcc1f98474b74c2863aca87.jpg, createdBy=068d2446376, createdName=Dr Z, createdTime=Fri Nov 22 07:07:55 CST 2019, time=2019-11-22, status=1, ipAttribution=)]
    2019-11-23 若水129

    #孤儿药物认定#

    0

  8. 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time=2019-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375637, encodeId=6c6f3e56373e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/08/03/0e492dda8bcc1f98474b74c2863aca87.jpg, createdBy=068d2446376, createdName=Dr Z, createdTime=Fri Nov 22 07:07:55 CST 2019, time=2019-11-22, status=1, ipAttribution=)]
    2019-11-22 lovetcm

    当年上海交大曹谊林教授在老鼠背上长出人耳朵，原理相似，可惜后来似乎没有往药方面发展

    0

  9. 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23 02:09:00 CST 2019, time=2019-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1362311, encodeId=6242136231118, content=<a href='/topic/show?id=9857e03444b' target=_blank style='color:#2F92EE;'>#畸形#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70344, encryptionId=9857e03444b, topicName=畸形)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca20190, createdName=wushaoling, createdTime=Sat Nov 23 02:09:00 CST 2019, time=2019-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1615968, encodeId=f2a21615968f7, content=<a href='/topic/show?id=519345433ea' target=_blank style='color:#2F92EE;'>#孤儿药物认定#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45433, encryptionId=519345433ea, topicName=孤儿药物认定)], attachment=null, 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time=2019-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375637, encodeId=6c6f3e56373e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/08/03/0e492dda8bcc1f98474b74c2863aca87.jpg, createdBy=068d2446376, createdName=Dr Z, createdTime=Fri Nov 22 07:07:55 CST 2019, time=2019-11-22, status=1, ipAttribution=)]
    2019-11-22 thm112988

    好

    0

  10. 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time=2019-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375637, encodeId=6c6f3e56373e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/08/03/0e492dda8bcc1f98474b74c2863aca87.jpg, createdBy=068d2446376, createdName=Dr Z, createdTime=Fri Nov 22 07:07:55 CST 2019, time=2019-11-22, status=1, ipAttribution=)]
    2019-11-22 Dr Z

    学习了

    0

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