JAHA:主动脉钙化与冠状动脉粥样硬化的发生相关!

2017-04-03 xing.T MedSci原创

由此可见,TAC和CAC共享着类似的发生钙化的主要决定因素。TAC参与者,特别是升TAC的参与者,发展为CAC的风险升高。

胸主动脉钙化(TAC)和冠状动脉钙化(CAC)是亚临床动脉粥样硬化的标志物,并且与主要血管事件的发生相关。近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员调查了TAC发生和进展的主要决定因素,以及TAC和CAC发病和进展之间的相关性。

在一个以人群为基础的队列研究中,3270名参与者(45-74岁,53.1%为女性)在基线和平均随访了5.1±0.3年后进行了心脏计算机断层扫描以量化升主动脉(ATAC)和降主动脉(DTAC)钙化情况以及CAC。多变量相对风险回归分析被用来评估心血管危险因素与TAC发生之间的相关性,基础TAC与CAC发生之间的相关性,以及基础CAC与TAC发生之间的相关性。

1243名参与者基础TAC为0例,随访5年后517名(41.6%)参与者发生TAC。降TAC的发病率(34.5%)高于比升TAC(23.3%)。5年后TAC发生与年龄(每5年相对风险为1.26 [95%可信区间(CI)为1.21-1.33])、血压(每10mmHg的相对风险为1.06,95% CI为1.03-1.10)、低密度脂蛋白胆固醇(每20mg/dL的相对风险为1.08,95%CI为1.04-1.12)、吸烟(相对风险为1.28,95%CI为1.07-1.53)。在没有基础CAC的1185名参与者中,当存在基础TAC时,发展为CAC的风险为28.3%,相比于不存在基础TAC的参与者为22.2%(超额风险为6.1%,95%CI为1.2-11.0%)。对CAC发生的过度风险点估计在升TAC中更高(10.8%,95%CI为4.8-16.7%,而在降TAC中较低(1.8%,95%CI为3.2%-6.7%)。在存在基础CAC的参与者中发展为升TAC和降TAC的超额风险分别为16.4%(95%CI为12.7-20%)和15.6%(95%CI为10.8-20.4%)。

由此可见,TAC和CAC共享着类似的发生钙化的主要决定因素。TAC参与者,特别是升TAC的参与者,发展为CAC的风险升高。

原始出处:


Hagen Kälsch, et al. Aortic Calcification Onset and Progression: Association With the Development of Coronary Atherosclerosis.JAHA.2017.https://doi.org/10.1161/JAHA.116.005093

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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185374, encodeId=63591853e4e8, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:33:56 CST 2017, time=2017-04-05, status=1, ipAttribution=)]
    2017-04-06 liur63

    学习了谢谢!

    0

  4. 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createdBy=3d1d25597695, createdName=1249897bm45(暂无昵称), createdTime=Mon Sep 04 14:29:00 CST 2017, time=2017-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185616, encodeId=1bbd18561669, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Thu Apr 06 22:43:45 CST 2017, time=2017-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185387, encodeId=119f18538e12, content=文章不错,值得分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Apr 05 21:54:19 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185379, encodeId=6b761853e9f9, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:40 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185378, encodeId=6a9d1853e8a5, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:32 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185377, encodeId=ac2b1853e7d6, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:23 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185376, encodeId=54951853e6b4, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:15 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185375, encodeId=db7f1853e528, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:05 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185374, encodeId=63591853e4e8, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:33:56 CST 2017, time=2017-04-05, status=1, ipAttribution=)]
    2017-04-05 1e10c84am36(暂无匿称)

    文章不错,值得分享

    0

  5. 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Apr 05 21:54:19 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185379, encodeId=6b761853e9f9, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:40 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185378, encodeId=6a9d1853e8a5, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, 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content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:15 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185375, encodeId=db7f1853e528, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:05 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185374, encodeId=63591853e4e8, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:33:56 CST 2017, time=2017-04-05, status=1, ipAttribution=)]
    2017-04-05 liur63

    学习了谢谢!

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1944445, encodeId=a1bc19444459f, content=<a href='/topic/show?id=411de6300ad' target=_blank style='color:#2F92EE;'>#粥样硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76300, encryptionId=411de6300ad, topicName=粥样硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b30d401, createdName=huangshifeng, createdTime=Wed Jul 12 01:29:00 CST 2017, time=2017-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1663266, encodeId=941b1663266de, content=<a href='/topic/show?id=4bae3334873' target=_blank style='color:#2F92EE;'>#动脉钙化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33348, encryptionId=4bae3334873, topicName=动脉钙化)], attachment=null, authenticateStatus=null, createdAvatar=null, 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:32 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185377, encodeId=ac2b1853e7d6, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:23 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185376, encodeId=54951853e6b4, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:15 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185375, encodeId=db7f1853e528, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:05 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185374, encodeId=63591853e4e8, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:33:56 CST 2017, time=2017-04-05, status=1, ipAttribution=)]
    2017-04-05 liur63

    学习了谢谢!

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1944445, encodeId=a1bc19444459f, content=<a href='/topic/show?id=411de6300ad' target=_blank style='color:#2F92EE;'>#粥样硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76300, encryptionId=411de6300ad, topicName=粥样硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b30d401, createdName=huangshifeng, createdTime=Wed Jul 12 01:29:00 CST 2017, time=2017-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1663266, encodeId=941b1663266de, content=<a href='/topic/show?id=4bae3334873' target=_blank style='color:#2F92EE;'>#动脉钙化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33348, encryptionId=4bae3334873, topicName=动脉钙化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d1d25597695, createdName=1249897bm45(暂无昵称), createdTime=Mon Sep 04 14:29:00 CST 2017, time=2017-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185616, encodeId=1bbd18561669, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Thu Apr 06 22:43:45 CST 2017, time=2017-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185387, encodeId=119f18538e12, content=文章不错,值得分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Apr 05 21:54:19 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185379, encodeId=6b761853e9f9, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:40 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185378, encodeId=6a9d1853e8a5, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:32 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185377, encodeId=ac2b1853e7d6, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:23 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185376, encodeId=54951853e6b4, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:15 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185375, encodeId=db7f1853e528, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:05 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185374, encodeId=63591853e4e8, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:33:56 CST 2017, time=2017-04-05, status=1, ipAttribution=)]
    2017-04-05 liur63

    学习了谢谢!

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1944445, encodeId=a1bc19444459f, content=<a href='/topic/show?id=411de6300ad' target=_blank style='color:#2F92EE;'>#粥样硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76300, encryptionId=411de6300ad, topicName=粥样硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b30d401, createdName=huangshifeng, createdTime=Wed Jul 12 01:29:00 CST 2017, time=2017-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1663266, encodeId=941b1663266de, content=<a href='/topic/show?id=4bae3334873' target=_blank style='color:#2F92EE;'>#动脉钙化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33348, encryptionId=4bae3334873, topicName=动脉钙化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d1d25597695, createdName=1249897bm45(暂无昵称), createdTime=Mon Sep 04 14:29:00 CST 2017, time=2017-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185616, encodeId=1bbd18561669, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Thu Apr 06 22:43:45 CST 2017, time=2017-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185387, encodeId=119f18538e12, content=文章不错,值得分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Apr 05 21:54:19 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185379, encodeId=6b761853e9f9, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:40 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185378, encodeId=6a9d1853e8a5, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:32 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185377, encodeId=ac2b1853e7d6, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:23 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185376, encodeId=54951853e6b4, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:15 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185375, encodeId=db7f1853e528, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:05 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185374, encodeId=63591853e4e8, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:33:56 CST 2017, time=2017-04-05, status=1, ipAttribution=)]
    2017-04-05 liur63

    学习了谢谢!

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1944445, encodeId=a1bc19444459f, content=<a href='/topic/show?id=411de6300ad' target=_blank style='color:#2F92EE;'>#粥样硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76300, encryptionId=411de6300ad, topicName=粥样硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b30d401, createdName=huangshifeng, createdTime=Wed Jul 12 01:29:00 CST 2017, time=2017-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1663266, encodeId=941b1663266de, content=<a href='/topic/show?id=4bae3334873' target=_blank style='color:#2F92EE;'>#动脉钙化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33348, encryptionId=4bae3334873, topicName=动脉钙化)], attachment=null, authenticateStatus=null, createdAvatar=null, 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Apr 05 21:54:19 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185379, encodeId=6b761853e9f9, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:40 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185378, encodeId=6a9d1853e8a5, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:32 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185377, encodeId=ac2b1853e7d6, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:23 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185376, encodeId=54951853e6b4, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:15 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185375, encodeId=db7f1853e528, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:05 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185374, encodeId=63591853e4e8, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:33:56 CST 2017, time=2017-04-05, status=1, ipAttribution=)]
    2017-04-05 liur63

    学习了谢谢!

    0

  10. 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Apr 05 21:54:19 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185379, encodeId=6b761853e9f9, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:34:40 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185378, encodeId=6a9d1853e8a5, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185374, encodeId=63591853e4e8, content=学习了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuLkkiaEa1J4A8RpxoFZ1V1SxXfAZoXeffWFsO8s5qTklzZa8iasdibic8OcUkdCpTyFeWuy5KePlj8Sm/0, createdBy=c4372036703, createdName=liur63, createdTime=Wed Apr 05 20:33:56 CST 2017, time=2017-04-05, status=1, ipAttribution=)]
    2017-04-05 liur63

    学习了谢谢!

    0