Eur J Neurol:右侧岛叶梗死与卒中后死亡率增加相关

2016-10-31 MedSci MedSci原创

背景:许多研究描述岛叶梗死与死亡率之间的相关性。通常包括脑岛的大梗死与病灶大小与死亡率相关。研究者推测,岛叶梗死独立于病变体积与和死亡率相关。方法: 研究者纳入了1000plus数据库中,2008年9月1号至2012年11月11号期间,发病1天DWI上显示有急性梗塞灶的卒中患者,并对其随访90天。应用卒中缺损软件评估岛叶梗塞的位置。在多因素Cox回归分析(因变量:死亡),研究者校正岛叶梗塞,年龄,

背景:许多研究描述岛叶梗死与死亡率之间的相关性。通常包括脑岛的大梗死与病灶大小与死亡率相关。研究者推测,岛叶梗死独立于病变体积与和死亡率相关。

方法: 研究者纳入了1000plus数据库中,2008年9月1号至2012年11月11号期间,发病1天DWI上显示有急性梗塞灶的卒中患者,并对其随访90天。应用卒中缺损软件评估岛叶梗塞的位置。在多因素Cox回归分析(因变量:死亡),研究者校正岛叶梗塞,年龄,梗塞体积,房颤病史,NIHSS分数及卒中史。

结果:研究包括736例患者,其中168例患者为岛性梗死。在随访时间的中位数为107天,岛叶梗死患者的累计生存率为90%,无岛叶梗死的患者为99%(P<0.001)。右侧岛叶梗死与死亡率独立相关(HR,2.60;CI,1.3-5.4;P = 0.010)。

结论:本研究中,右侧岛叶梗死是缺血性卒中后死亡率的预测指标。对患者的选择偏差值得进一步研究。

原始出处:

Hanne L, Brunecker P, et al. Right insular infarction and mortality after ischaemic stroke. Eur J Neurol. 2016 Sep 19.


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    2017-05-16 yinhl1978
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  3. [GetPortalCommentsPageByObjectIdResponse(id=1999772, encodeId=adf81999e724b, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Tue May 16 06:53:00 CST 2017, time=2017-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1671268, encodeId=6a9816e12687f, content=<a href='/topic/show?id=9f4e360191a' target=_blank style='color:#2F92EE;'>#卒中后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36019, encryptionId=9f4e360191a, topicName=卒中后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ff7426824786, createdName=waiwai3039, createdTime=Tue Nov 15 06:53:00 CST 2016, time=2016-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=152822, encodeId=3dd815282226, content=原因是啥?, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Wed Nov 02 07:29:20 CST 2016, time=2016-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=152821, encodeId=498515282140, content=又学习了~, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Wed Nov 02 07:28:48 CST 2016, time=2016-11-02, status=1, ipAttribution=)]
    2016-11-02 保守主义

    原因是啥?

    0

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    2016-11-02 保守主义

    又学习了~

    0