Radiology:心脏MRI心室间隔角识别高危毛细血管前后肺动脉高压的价值

2018-11-17 shaosai MedSci原创

本研究旨在评价心室间隔(IVS)角在识别左心室病变所致肺动脉高压(PH)患者毛细血管前后肺动脉高压(Cpc-PH)的价值。

本研究旨在评价心室间隔(IVS)角在识别左心室病变所致肺动脉高压(PH)患者毛细血管前后肺动脉高压(Cpc-PH)的价值。

本研究收集了PH并当天行右心室导管插入术(RHC)和MRI的患者,利用ROC曲线、敏感性、特异性、阴性和阳性预测值评价IVS角对Cpc-PH合并肺动脉楔压超过15 mmHg的患者。利用Cox单变量和多变量比例危害回归评价IVS角作为全因死亡率的指标。

结果为,工哟708例患者同日行MRI和RHC,171患者PAWP超过15 mmHg。平均年龄为70岁(范围为21-90岁)。收缩压IVS较与舒张压梯度(DPG)具有相关性(r = 0.739, P < .001)。ROC曲线分析表明间隔角有助于识别Cpc-PH (DPG ≥ 7),曲线下面积为0.911 (P < .001)。160°作为识别7 mmHg DPG的最佳截断值,敏感性和特异性分别为67%、93%。IVS较能够预测全因死亡率(标准HR=1.615; P < .01)。

本研究表明,在毛细血管前后肺动脉高压患者中收缩期室间隔角增大,有助于预测左心室病变所致PH患者死亡率增高。

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    2018-11-18 xfpan13
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    2018-11-17 明天jing

    肺动脉高压表面是罕见病,事实上临床上并不少见,治疗药物虽然有一些,但是整体仍然不理解,可能未来需要采用综合治疗措施。

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