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日本批准在动物体内培育人类脏器的研究项目

2019-07-26 新华网 新华网

人类脏器
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日本政府近日批准利用诱导多能干细胞（iPS细胞）在实验鼠体内培育人类胰脏的研究项目。这是日本首个申请利用动物培育人类脏器的研究项目。据日本共同社等媒体报道，日本文部科学省一个专门委员会24日批准了东京大学一个研究小组提出的上述研究计划。研究小组并未透露项目开展的具体时间，日本媒体报道称研究将于近期实施，以确认利用相关技术能否在动物体内正常形成脏器，希望将来能为移植医疗提供助力。研究人员将首先对实验

日本政府近日批准利用诱导多能干细胞（iPS细胞）在实验鼠体内培育人类胰脏的研究项目。这是日本首个申请利用动物培育人类脏器的研究项目。

据日本共同社等媒体报道，日本文部科学省一个专门委员会24日批准了东京大学一个研究小组提出的上述研究计划。研究小组并未透露项目开展的具体时间，日本媒体报道称研究将于近期实施，以确认利用相关技术能否在动物体内正常形成脏器，希望将来能为移植医疗提供助力。

研究人员将首先对实验鼠受精卵的基因进行修改，使其无法正常生成自身的胰脏等脏器；然后向受精卵中植入人类iPS细胞，培育含有人类细胞的动物胚胎“动物性集合胚”；之后再将其移植回实验鼠子宫。研究人员期待实验鼠胎鼠长大后能拥有由人类iPS细胞形成的胰脏等。

据报道，日本研究人员还将在食蟹猴和猪的受精卵中植入人类iPS细胞，但暂时不会将其移植回子宫，而只是开展有关iPS细胞的研究。

日本文部科学省今年3月修改了有关规定，允许在动物体内培育人类器官，以加强利用动物培育移植用人体器官的相关研究。

iPS细胞是通过对成熟体细胞“重新编程”培育出的干细胞，拥有与胚胎干细胞相似的分化潜力，但获得方法相对简单，并且避开了胚胎干细胞研究中的伦理问题，在临床治疗中被认为具有巨大应用价值。

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1294485, encodeId=3d751294485f1, content=<a href='/topic/show?id=ca6e592189b' target=_blank style='color:#2F92EE;'>#日本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59218, encryptionId=ca6e592189b, topicName=日本)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Sun Jul 28 01:05:00 CST 2019, time=2019-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370291, encodeId=17c63e02916d, content=终于, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8175103766, createdName=145fd56em38暂无昵称, createdTime=Fri Jul 26 12:08:53 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370287, encodeId=bcb13e028793, content=向科研人员致敬！, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e5171668917, createdName=坚强007, createdTime=Fri Jul 26 10:40:43 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370286, encodeId=108b3e02860e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1bb241978, createdName=phoebeyan520, createdTime=Fri Jul 26 10:32:21 CST 2019, time=2019-07-26, status=1, ipAttribution=)]
    2019-07-28 chentianping

    #日本#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1294485, encodeId=3d751294485f1, content=<a href='/topic/show?id=ca6e592189b' target=_blank style='color:#2F92EE;'>#日本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59218, encryptionId=ca6e592189b, topicName=日本)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Sun Jul 28 01:05:00 CST 2019, time=2019-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370291, encodeId=17c63e02916d, content=终于, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8175103766, createdName=145fd56em38暂无昵称, createdTime=Fri Jul 26 12:08:53 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370287, encodeId=bcb13e028793, content=向科研人员致敬！, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e5171668917, createdName=坚强007, createdTime=Fri Jul 26 10:40:43 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370286, encodeId=108b3e02860e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1bb241978, createdName=phoebeyan520, createdTime=Fri Jul 26 10:32:21 CST 2019, time=2019-07-26, status=1, ipAttribution=)]
    2019-07-26 145fd56em38暂无昵称

    终于

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1294485, encodeId=3d751294485f1, content=<a href='/topic/show?id=ca6e592189b' target=_blank style='color:#2F92EE;'>#日本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59218, encryptionId=ca6e592189b, topicName=日本)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Sun Jul 28 01:05:00 CST 2019, time=2019-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370291, encodeId=17c63e02916d, content=终于, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8175103766, createdName=145fd56em38暂无昵称, createdTime=Fri Jul 26 12:08:53 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370287, encodeId=bcb13e028793, content=向科研人员致敬！, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e5171668917, createdName=坚强007, createdTime=Fri Jul 26 10:40:43 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370286, encodeId=108b3e02860e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1bb241978, createdName=phoebeyan520, createdTime=Fri Jul 26 10:32:21 CST 2019, time=2019-07-26, status=1, ipAttribution=)]
    2019-07-26 坚强007

    向科研人员致敬！

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1294485, encodeId=3d751294485f1, content=<a href='/topic/show?id=ca6e592189b' target=_blank style='color:#2F92EE;'>#日本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59218, encryptionId=ca6e592189b, topicName=日本)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Sun Jul 28 01:05:00 CST 2019, time=2019-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370291, encodeId=17c63e02916d, content=终于, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8175103766, createdName=145fd56em38暂无昵称, createdTime=Fri Jul 26 12:08:53 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370287, encodeId=bcb13e028793, content=向科研人员致敬！, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e5171668917, createdName=坚强007, createdTime=Fri Jul 26 10:40:43 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370286, encodeId=108b3e02860e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1bb241978, createdName=phoebeyan520, createdTime=Fri Jul 26 10:32:21 CST 2019, time=2019-07-26, status=1, ipAttribution=)]
    2019-07-26 phoebeyan520

    学习了

    0