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Br J Dermatol：下肢毛细血管畸形的儿童中，临床和血流动力学因素与长短腿相关

2017-10-11 xiaoxiao MedSci原创

长短腿毛细血管畸形
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背景：血管畸形(vascular malformations) 正常内皮细胞的血管畸形。可发生于毛细血管、静脉、淋巴管、动脉及多种管腔。发生于毛细血管内被称为毛细血管畸形（capillary malformation，CM）。遗传学发现使人们更好地了解随过度发育综合征而产生的毛细血管畸形（CMS）。然而，目前的可以水平还不足以普及分子分析。因此，需要其他的分析方法来更好地监控毛细血管畸形。目的：本

背景：血管畸形(vascular malformations) 正常内皮细胞的血管畸形。可发生于毛细血管、静脉、淋巴管、动脉及多种管腔。发生于毛细血管内被称为毛细血管畸形（capillary malformation，CM）。遗传学发现使人们更好地了解随过度发育综合征而产生的毛细血管畸形（CMS）。然而，目前的可以水平还不足以普及分子分析。因此，需要其他的分析方法来更好地监控毛细血管畸形。目的：本研究旨在在下肢CM的儿童中确定长短脚（LLD）是否与临床和血流动力学因素相关。方法：研究人员从CONAPE队列研究中获得2到12岁的下肢CM儿童的相关数据，该队列是一项多中心队列研究，全称是COhorte Nationale d'enfants atteints d'Angiome Plan de membrE inférieur。该研究前瞻性地收集了患儿们的临床特征。患儿们曾接受过(用于检查人体内脏或胎儿发育的)超声波回声检查仪（能计算计算动脉血流量，即ABF）测定双下肢的血流动力学因素。双下肢之间的ABF差异≥50%时，研究人员认为存在相关性。基于X光照片由同一个超声科医师来鉴定LLD≥2

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    2018-03-29 12498ca5m93暂无昵称

    #血管畸形#

    0

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    2018-04-23 ymljack

    #毛细血管畸形#

    0

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    2017-11-30 仁心济世

    #血流动力#

    0

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    2017-11-12 wshxjq

    #毛细血管#

    0

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    2017-10-13 wushaoling

    #畸形#

    0

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    2017-10-13 zjshifan_98647306

    #血流动力学#

    0

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    2017-10-12 131****2916

    不错的文章值得推荐

    0

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    2017-10-12 飛歌

    学习了很有用

    0

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    2017-10-11 changjiu

    学习了.谢谢

    0