JAMA:严重创伤患者院前输血可降低死亡风险

2017-10-25 zhangfan MedSci原创

研究认为,对于严重创伤伤员,尽快的院外输血可显著降低其24小时和30天的死亡风险

院前急救输血对创伤急救护理的意义目前尚不清楚。近日研究人员考察了院前急救输血和开始时间与预后的关系。

研究人员对2012-15年美军阿富汗战争中的伤亡数据进行了分析,膝盖或肘部创伤性截肢伤员、收缩低于90 mm Hg以及心率超过120每分的休克伤员参与。研究的主要终点是24小时以及30天后的死亡率。

502名伤员参与研究,平均年龄25岁,男性占98%,院前急救输血伤员55人,未输血伤员447人。研究发现,输血组3名伤员(5%)以及未输血组85名(19%)伤员在24小时内死亡,组间差异为14%。30天后,6名输血伤员(11%)和102名(23%)非输血伤员死亡,组间差异为12%,院前急救输血后重伤伤员24小时的死亡风险为0.26,30天的死亡风险为0.39。受伤后第一时间内输血对于患者死亡风险降低至关重要,开始院内医疗措施(平均受伤后36分钟)前15分钟输血的伤员相对于延迟输血伤员其死亡率大大降低,分别为3.2%和21.0%。

研究认为,对于严重创伤伤员,尽快的院外输血可显著降低其24小时和30天的死亡风险。

原始出处:


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    2018-06-03 仁医06
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    2017-10-27 windight
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