J Am Geriatrics Soc:老年患者降压,只有“衰弱”者血压才应≥150/90 mmHg

2017-04-03 朱朱 中国循环杂志

既往研究已证实,高血压可导致死亡风险增加。但美国一项研究表明,血压≥150 /90 mmHg的虚弱老人,死亡风险较低,尤其是握力较弱且走路慢者。 女性握力<16 kg、男性<26 kg视为握力较弱,反之则握力正常;走路慢是指女性步行速度<0.6米/秒,男性<0.52米/秒,反之走路不慢。 校正混淆因素后,在握力较弱的老年人中,收缩压和舒张压升高的人,死亡风险分别


既往研究已证实,高血压可导致死亡风险增加。但美国一项研究表明,血压≥150 /90 mmHg的虚弱老人,死亡风险较低,尤其是握力较弱且走路慢者。

女性握力<16 kg、男性<26 kg视为握力较弱,反之则握力正常;走路慢是指女性步行速度<0.6米/秒,男性<0.52米/秒,反之走路不慢。

校正混淆因素后,在握力较弱的老年人中,收缩压和舒张压升高的人,死亡风险分别降低了6%和16%。在握力较弱且走路慢的老年人中,死亡风险分别降低15%和47%。相反,如果握力正常或走路不慢,血压较高的人死亡风险增加。

这提示,对于比较衰弱的老年人,降压治疗要特殊对待,降压目标不能一刀切。

主要研究者Wu表示,“衰弱的老年人通常对降压药物的反应较差,把血压降到较低水平并不能使他们获益。”

他认为,这与个体化治疗的理想是一致的,对待老年患者不能仅考虑年龄,还要考虑其身体功能状态。

这项研究纳入了7492例年龄≥65岁的受试者,随访6年期间,1/4的受试者死亡。

原始出处:

Wu C, Smit E, Peralta CA, Sarathy H, Odden MC. Functional Status Modifies the Association of Blood Pressure with Death in Elders: Health and Retirement Study, J Am Geriatrics Soc, First published: 17March 2017

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    0

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    2017-04-04 虈亣靌

    学习了谢谢作者分享!

    0

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    2017-04-04 tofsw

    学习了谢谢分享

    0

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    2017-04-04 往日如昨

    学习了谢谢分享

    0

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    2017-04-04 ylzr123

    反复实践,反复学习,认真推敲,不断提高自己的业务水平。

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    2017-04-03 榄枷檬

    对待老年患者不能仅考虑年龄,还要考虑其身体功能状态。

    0

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