J Periodontol:患牙龈炎的肥胖儿童龈沟液、唾液抵抗素和肿瘤坏死因子-α水平的研究

2018-06-03 MedSci MedSci原创

本研究旨在评估患牙龈炎的肥胖儿童龈沟液(GCF)和唾液中抵抗素和肿瘤坏死因子-α(TNF-α)的水平。

本研究旨在评估患牙龈炎的肥胖儿童龈沟液(GCF)和唾液中抵抗素和肿瘤坏死因子-α(TNF-α)的水平。

实验纳入130名儿童(65名肥胖者和65名正常体重;8-12岁)进行研究。根据孩子的体重和牙周状况分为四个亚组, 1)患有牙龈炎的肥胖儿童(OG,n = 33); 2)牙周健康(OH,n = 32)的肥胖儿童; 3)体重正常的牙龈炎儿童(NWG,n = 32); 4)牙周健康的正常体重儿童(NWH,n = 33)。记录体重指数(BMI)百分位数,探诊深度(PPD),牙龈指数(GI)和菌斑指数(PI)。通过ELISA分析GCF和唾液样本中的抵抗素和TNF-α。

结果:肥胖儿童的体重指数百分比高于正常体重儿童(p <0001)。 PPD,GI,PI,GCF量,GCF和唾液抵抗素与TNF-α水平在肥胖儿童和正常体重儿童之间相似(P> 0.05)。 OG和NWG亚组的GI,PI,GCF量,GCF抵抗素总量和唾液抵抗素浓度显着高于OH和NWH组,但GCF抵抗素和TNF-α浓度低于(P <0.0001)OH和NWH组。 GCF抵抗素总量与GI,PI和GCF TNF-α总量呈正相关(P <0.05)。

在牙龈炎的情况下,肥胖与儿童GCF和唾液中的抵抗素和TNF-α水平无关。

原始出处:

Dogusal G, et al. Gingival crevicular fluid and salivary resistin and tumor necrosis factor-alpha levels in obese children with gingivitis. Journal of Periodontology. 2018 April. doi:10.1002/JPER.17-0613

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    2018-06-05 millore
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    2018-06-03 惠映实验室

    学习了.谢谢分享.

    0

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本实验旨在评估患有慢性牙周炎的HIV感染者HLA-B57.01(人类白细胞抗原)与牙周临床参数之间的关系。

J Periodontol: 慢性和侵袭性牙周炎患者牙龈组织中干扰素-λ的表达

一些研究已经证明慢性和侵袭性牙周炎患者牙周袋中存在疱疹病毒。最近发现,干扰素λ(IFN-λ)具有抗病毒特性并且由疱疹病毒诱导。本研究旨在定量分析慢性和侵袭性牙周炎患者牙龈组织中IFN-λs(IFN-λ1,IFN-λ2,IFN-λ3)的mRNA表达。

J Periodontol:睾酮长期耗竭可以减轻结扎性牙周炎的骨吸收

已知,睾酮会在生理和病理条件下影响骨骼。本研究旨在评估睾酮在大鼠实验性牙周炎中的作用。