Environ Int:在2个欧洲群体中,空气污染和鼻炎发生率之间相关性研究

2018-04-08 AlexYang MedSci原创

污染和鼻炎之间的相关性并没有很好被研究。最近,有研究人员对受试者家庭地址的建模的空气污染和自我报道的鼻炎发生率之间的相关性进行了纵向分析。研究人员使用的数据来自2个多中心群体研究的1533名成年人(EGEA和ECRHS)。鼻炎发生率被定义为在第二次跟踪调查报道鼻炎(2011年到2013年)而不是在第一次跟踪调查时(2000年到2007年)。研究人员利用在2009年到2010年期间,由ESCAPE计

污染和鼻炎之间的相关性并没有很好被研究。最近,有研究人员对受试者家庭地址的建模的空气污染和自我报道的鼻炎发生率之间的相关性进行了纵向分析。研究人员使用的数据来自2个多中心群体研究的1533名成年人(EGEA和ECRHS)。鼻炎发生率被定义为在第二次跟踪调查报道鼻炎(2011年到2013年)而不是在第一次跟踪调查时(2000年到2007年)。研究人员利用在2009年到2010年期间,由ESCAPE计划开发的地上使用回归模型评估了参与者家庭住址对NO2, PM10 和PM2.5的年度暴露水平,并利用泊松回归推算了发生率比例(IRR),还利用城市和多元回归测试的混合分析对异质性进行了相关研究。

研究发现,在NO2增加10μg·m-3(aIRR 1.00 [0.91-1.09])和PM2.5增加 5μg·m-3(aIRR 0.88 [0.73-1.04])时,长期的空气污染接触和鼻炎发生率之间没有发现相关性。另外,研究人员在2个污染模型中发现了相似的结果(NO2增加10μg·m-3 : aIRR 1.01 [0.87-1.17]; PM2.5增加5μg·m-3 :aIRR 0.87 [0.68-1.08)。结果根据城市的不同而有所差异,但是对任何一种污染物,都没有出现区域性分布。

最后,研究人员指出,他们的研究在长期空气污染和鼻炎发生率两者之间没有发现任何相关性的一致性证据。

原始出处:

Burte E, Leynaert B, Bono R et al. Association between air pollution and rhinitis incidence in two European cohorts. Environ Int. 29 Mar 2018.

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    2018-09-05 xjy13
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    2018-04-10 july_979

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