Clin Oral Investig:预防牙髓再生治疗导致牙冠变色的体外模型研究

2017-11-13 lishiting MedSci原创

这篇研究的目的是在一个体外模型中,评估牙本质粘接剂(DBA)封闭牙髓再生治疗(REPs)后髓室壁的防止牙变色效果。

这篇研究的目的是在一个体外模型中,评估牙本质粘接剂(DBA)封闭牙髓再生治疗(REPs)后髓室壁的防止牙变色效果。研究选取96颗牛的切牙进行预备,并随机分为2组。一个组的髓室壁通过DBA进行封闭,随后根管内放置3倍的包含米诺环素的抗生素糊剂(TAP);另一组不使用DBA。4周后,根管内注入人全血,并且每组再按照覆盖血块上的牙髓材料的不同(ProRoot MTA, OrthoMTA, RetroMTA或Biodentine)随机分为2个亚组(n = 12)。在不同的阶段测量颜色变化(?E)。数据使用t检验和two-way ANOVA进行统计学分析。结果显示,髓室壁使用DBA封闭的样本在再生治疗的每一个阶段牙冠变色的程度均较弱(p < 0.001)。然而,临床应用DBA在视差上并不能完全防止牙冠颜色的变化。血块上覆盖不同的牙髓材料并不会引起明显不同的牙冠变色(p > 0.05)。结论:TAP封药前封闭髓室壁,在使用不同牙髓材料进行REP后,可以减弱牙冠变色,但不能完全避免。临床意义:牙齿变色是REPs的一个不利结果。包含米诺环素的TAP会导致牙冠变色,甚至在髓室壁封闭后。由此,

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    2018-04-21 jxrzshh
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    2018-03-17 小几洁
  4. 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createdBy=5eeb26562774, createdName=jxrzshh, createdTime=Sat Apr 21 18:05:00 CST 2018, time=2018-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020282, encodeId=2d4c202028236, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Sat Mar 17 08:05:00 CST 2018, time=2018-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1973409, encodeId=fdc519e340999, content=<a href='/topic/show?id=fb846e6644b' target=_blank style='color:#2F92EE;'>#牙髓再生治疗#</a>, beContent=null, 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CST 2017, time=2017-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261074, encodeId=19852610e4d0, content=不错了.学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Mon Nov 13 21:56:59 CST 2017, time=2017-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261068, encodeId=179826106875, content=学习了.好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, 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  5. 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objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67664, encryptionId=fb846e6644b, topicName=牙髓再生治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=101c2500074, createdName=124987e8m07暂无昵称, createdTime=Sun Nov 19 03:05:00 CST 2017, time=2017-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050913, encodeId=4d632050913e1, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Tue Dec 12 23:05:00 CST 2017, time=2017-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261769, 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createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Mon Nov 13 21:46:25 CST 2017, time=2017-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261061, encodeId=caf9261061ed, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/iatia2cT76F0wiceqgFicEXqwC1iaC4mwmVOR9onEYJ9mHKVUHx8tqoPbJiakAIzgut3SdoQspXkbPY9FiabzE14IusDA/132, createdBy=60641826220, createdName=huizi3382, createdTime=Mon Nov 13 21:09:44 CST 2017, time=2017-11-13, status=1, ipAttribution=)]
  6. 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createdBy=5eeb26562774, createdName=jxrzshh, createdTime=Sat Apr 21 18:05:00 CST 2018, time=2018-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020282, encodeId=2d4c202028236, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Sat Mar 17 08:05:00 CST 2018, time=2018-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1973409, encodeId=fdc519e340999, content=<a href='/topic/show?id=fb846e6644b' target=_blank style='color:#2F92EE;'>#牙髓再生治疗#</a>, beContent=null, 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encodeId=8f4f261e69d8, content=学习了.谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Thu Nov 16 19:31:59 CST 2017, time=2017-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417496, encodeId=abe2141e4960e, content=<a href='/topic/show?id=84ff6e663c4' target=_blank style='color:#2F92EE;'>#牙髓再生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67663, encryptionId=84ff6e663c4, topicName=牙髓再生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cf73291723, createdName=zhixianchen, createdTime=Wed Nov 15 12:05:00 CST 2017, time=2017-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261074, encodeId=19852610e4d0, content=不错了.学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Mon Nov 13 21:56:59 CST 2017, time=2017-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261068, encodeId=179826106875, content=学习了.好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Mon Nov 13 21:46:25 CST 2017, time=2017-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261061, encodeId=caf9261061ed, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/iatia2cT76F0wiceqgFicEXqwC1iaC4mwmVOR9onEYJ9mHKVUHx8tqoPbJiakAIzgut3SdoQspXkbPY9FiabzE14IusDA/132, createdBy=60641826220, createdName=huizi3382, createdTime=Mon Nov 13 21:09:44 CST 2017, time=2017-11-13, status=1, ipAttribution=)]
    2017-11-16 changjiu

    学习了.谢谢

    0

  7. 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  8. 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createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Mon Nov 13 21:46:25 CST 2017, time=2017-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261061, encodeId=caf9261061ed, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/iatia2cT76F0wiceqgFicEXqwC1iaC4mwmVOR9onEYJ9mHKVUHx8tqoPbJiakAIzgut3SdoQspXkbPY9FiabzE14IusDA/132, createdBy=60641826220, createdName=huizi3382, createdTime=Mon Nov 13 21:09:44 CST 2017, time=2017-11-13, status=1, ipAttribution=)]
    2017-11-13 中医痴

    不错了.学习了.谢谢分享!

    0

  9. 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createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Mon Nov 13 21:46:25 CST 2017, time=2017-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261061, encodeId=caf9261061ed, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/iatia2cT76F0wiceqgFicEXqwC1iaC4mwmVOR9onEYJ9mHKVUHx8tqoPbJiakAIzgut3SdoQspXkbPY9FiabzE14IusDA/132, createdBy=60641826220, createdName=huizi3382, createdTime=Mon Nov 13 21:09:44 CST 2017, time=2017-11-13, status=1, ipAttribution=)]
    2017-11-13 1ddf0692m34(暂无匿称)

    学习了.好文章

    0

  10. 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objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67664, encryptionId=fb846e6644b, topicName=牙髓再生治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=101c2500074, createdName=124987e8m07暂无昵称, createdTime=Sun Nov 19 03:05:00 CST 2017, time=2017-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050913, encodeId=4d632050913e1, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Tue Dec 12 23:05:00 CST 2017, time=2017-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261769, encodeId=8f4f261e69d8, content=学习了.谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Thu Nov 16 19:31:59 CST 2017, time=2017-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417496, encodeId=abe2141e4960e, content=<a href='/topic/show?id=84ff6e663c4' target=_blank style='color:#2F92EE;'>#牙髓再生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67663, encryptionId=84ff6e663c4, topicName=牙髓再生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cf73291723, createdName=zhixianchen, createdTime=Wed Nov 15 12:05:00 CST 2017, time=2017-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261074, encodeId=19852610e4d0, content=不错了.学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Mon Nov 13 21:56:59 CST 2017, time=2017-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261068, encodeId=179826106875, content=学习了.好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Mon Nov 13 21:46:25 CST 2017, time=2017-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261061, encodeId=caf9261061ed, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/iatia2cT76F0wiceqgFicEXqwC1iaC4mwmVOR9onEYJ9mHKVUHx8tqoPbJiakAIzgut3SdoQspXkbPY9FiabzE14IusDA/132, createdBy=60641826220, createdName=huizi3382, createdTime=Mon Nov 13 21:09:44 CST 2017, time=2017-11-13, status=1, ipAttribution=)]
    2017-11-13 huizi3382

    不错

    0