Ann Neurol: CT灌注成像用于风患者血管内治疗预后评估

2017-07-03 zhangfan MedSci原创

对于中风后18小时内进行血管内治疗的患者, CT灌注成像结果对预测患者预后表现出极高的准确性,是用于患者预后评价的潜在方法

近日研究人员考查了CT灌注成像在中风18小时内评估血管成形术效果以及患者预后的应用。

研究人员进行了一项多中心队列研究,对急性脑卒中患者在CT灌注后90分钟内进行血管内治疗。若基线CT灌注显示患者存在小的缺血核心和一个大的半影区则该患者定义为"目标不匹配"。再灌注被定义为基线CT灌注和36小时随访磁共振成像的临界低灌注至少减少了50%。

共190名患者在基线进行了CT灌注研究并进行了血管造影,患者平均年龄66 岁, 平均卒中病情评估[NIHSS]=16,从出现症状到血管内治疗平均时间5.2小时)。再灌注率为89%。对于标记为"目标不匹配"患者(n=131), 再灌注与良好临床反应(NIHSS分数提高8分以上)的可能性密切相关 (83% vs 44%; p=0.002,OR=6.6,95% CI=2.1-20.9)。对于在中风发作6小时内(OR=6.4,95% CI=1.5-27.8或6小时后(OR=13.7,95% CI=1.4-140)接受治疗的患者,相关性差异不显著。

研究显示,对于中风后18小时内进行血管内治疗的患者, CT灌注成像结果对预测患者预后表现出极高的准确性,是用于患者预后评价的潜在方法。

原始出处:


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    2018-06-15 yinhl1978
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    2017-07-03 杨利洪

    学习了,分享了

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1743539, encodeId=24c01e435398c, content=<a href='/topic/show?id=89691002006b' target=_blank style='color:#2F92EE;'>#预后评估#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100200, encryptionId=89691002006b, topicName=预后评估)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6d4335139306, createdName=yeye5224624, createdTime=Sat Oct 14 02:51:00 CST 2017, time=2017-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2000015, encodeId=4bad20000158a, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Fri Jun 15 08:51:00 CST 2018, time=2018-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988440, encodeId=720f198844088, content=<a href='/topic/show?id=7d62668e678' target=_blank style='color:#2F92EE;'>#灌注成像#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66876, encryptionId=7d62668e678, topicName=灌注成像)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7460166, createdName=zhang92560, createdTime=Sat Nov 25 21:51:00 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1946249, encodeId=710a19462490e, content=<a href='/topic/show?id=f12a54e15b' target=_blank style='color:#2F92EE;'>#CT灌注成像#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5471, encryptionId=f12a54e15b, topicName=CT灌注成像)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca282500032, createdName=1249857fm32暂无昵称, createdTime=Thu Apr 19 13:51:00 CST 2018, time=2018-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218188, encodeId=3078218188e4, content=学习了,分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Mon Jul 03 17:26:26 CST 2017, time=2017-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218176, encodeId=66902181e63f, content=研究显示,对于中风后18小时内进行血管内治疗的患者,CT灌注成像结果对预测患者预后表现出极高的准确性,是用于患者预后评价的潜在方法。, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Mon Jul 03 16:08:24 CST 2017, time=2017-07-03, status=1, ipAttribution=)]
    2017-07-03 有备才能无患

    研究显示,对于中风后18小时内进行血管内治疗的患者,CT灌注成像结果对预测患者预后表现出极高的准确性,是用于患者预后评价的潜在方法。

    0

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