Lancet Global Health:2018年全球5岁以下幼儿流感相关下呼吸道感染负担研究

2020-02-24 MedSci MedSci原创

研究认为,中低收入国家幼儿与流感相关的疾病负担沉重

季节性流感是幼儿急性下呼吸道感染(ALRI)的常见原因。2008年,研究人员估计全球5岁以下儿童发生了2000万起与流感病毒相关的ALRI,其中100万起为严重ALRI。近日研究人员对2018年全球5岁以下儿童流感病毒相关呼吸道感染负担进行了评估。

研究收集了1995-2018年间发表的相关研究中,以评估5岁以下儿童流感相关呼吸道感染的区域和全球负担,按严重程度、病例确定、区域和年龄估计流感病毒相关呼吸道感染的发病率和住院率。并估计了流感病毒ALRI的院内死亡率。同时根据医院内死亡人数、美国儿科流感相关死亡数据和基于人口的儿童全因肺炎死亡率数据,对中低收入国家的流感病毒相关ALRI死亡率进行评估。

2018年,在全球5岁以下儿童中,估计总计发生了1.09亿次流感发作,总计1010万例流感病毒相关的ALRI病例,导致87万次流感病毒相关的ALRI住院,住院死亡15300人,流感病毒相关的ALRI总死亡人数高达34800人。流感病毒占ALRI病因的7%,占ALRI住院病因的5%,占5岁以下ALRI儿童死亡的4%。大约23%的住院病人和36%的住院死亡病例是6个月以下的婴儿。大约82%的住院死亡发生在低收入和中低收入国家。

研究认为,中低收入国家幼儿与流感相关的疾病负担沉重。

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    2020-09-29 shizhenshan
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    2020-07-23 howi
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    2020-02-26 zhmscau
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