Circ Cardiovasc Interv:识别NSTEMI罪犯血管,心脏磁共振完胜冠脉造影

2019-05-16 卢芳 中国循环杂志

一项发表在Circulation子刊的前瞻性研究显示,就非ST段抬高型心肌梗死(NSTEMI)的罪犯病变发现而言,常规冠脉造影不敌延迟增强心脏磁共振成像(DE-CMR)。近1/3的NSTEMI患者,可通过磁共振识别出不同或新的罪犯病变。

一项发表在Circulation子刊的前瞻性研究显示,就非ST段抬高型心肌梗死(NSTEMI)的罪犯病变发现而言,常规冠脉造影不敌延迟增强心脏磁共振成像(DE-CMR)。近1/3的NSTEMI患者,可通过磁共振识别出不同或新的罪犯病变。

研究显示,在114例NSTEMI例患者中,冠脉造影对其中37%的患者中存在的梗死相关动脉“眼盲”,而磁共振则在其中60%的患者中发现梗死相关动脉,另外还在19%的患者中发现非冠脉病变。

即使在冠脉造影明确有梗死相关动脉的72例患者中,磁共振还可在其中14%的患者发现不同的梗死相关动脉,在其中12.5%的患者中发现非冠脉病变,包括7例有心肌炎、1例Takotsubo心肌病、1例心肌淀粉样变性。

总之,磁共振完胜冠脉造影,在31%的患者中发现新的梗死相关动脉,以及在15%的患者中发现非缺血病变。

55例接受血运重建的患者中,有15例(27%)患者在磁共振明确的非罪犯冠脉区域进行了血运重建。其中11例为不同的梗死相关动脉,4例为心肌炎或Takotsubo心肌病。



研究者认为,明确梗死相关动脉,或部分解释了仅罪犯血管血运重建或多支血管重建哪种最适合NSTEMI的矛盾性。

“也许进行多支血管血运重建效果好,就是因为恰好的梗死相关动脉被休整,不过这些先进行核磁共振检查就能做得更好了,也许仅单支血管进行血运重建才是最佳选择。这项研究或提示会产生不同的临床结局。”研究者表示。

这项研究中,最让研究者关注的是,每4例血运重建患者中就有1例支架置于磁共振明确的无梗死动脉中。也就是说,支架放错了地方。

研究者指出,这项研究提示,每个NSTEMI患者均行心脏磁共振检查跳跃较大,意味着NSTEMI患者管理方式的变革,但值得开展更大规模随机对照试验。

这项研究共纳入3个中心114例首次发作心梗的患者,入院后中位1.1天行磁共振,磁共振后中位4小时行冠脉造影。临床团队和介入医师均对磁共振检查结果毫不知情。

原始出处:Heitner JF, Senthilkumar A, Harrison JK, et al. Identifying the Infarct-Related Artery in Patients With Non-ST-Segment-Elevation Myocardial Infarction. Circ Cardiovasc Inte. 2019 May;12(5):e007305.

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    2019-08-01 quxin068
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    2020-02-04 drj2003
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    2019-05-19 HLL1980

    磁共振心脏检查,很多医院做不了

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1938937, encodeId=14a3193893e85, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Thu Aug 01 11:52:00 CST 2019, time=2019-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1977587, encodeId=241d19e75870b, content=<a href='/topic/show?id=d9e5130962f' target=_blank style='color:#2F92EE;'>#NST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13096, encryptionId=d9e5130962f, topicName=NST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=80c5136, createdName=drj2003, createdTime=Tue Feb 04 21:52:00 CST 2020, time=2020-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=366439, encodeId=3bba366439f3, content=磁共振心脏检查,很多医院做不了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c6d1682658, createdName=HLL1980, createdTime=Sun May 19 10:56:48 CST 2019, time=2019-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341660, encodeId=6cb91341660c6, content=<a href='/topic/show?id=24b8e37529a' target=_blank style='color:#2F92EE;'>#磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73752, encryptionId=24b8e37529a, topicName=磁共振)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24a22500182, createdName=1696533704_45270454, createdTime=Fri May 17 15:52:00 CST 2019, time=2019-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1401461, encodeId=5dcb140146159, content=<a href='/topic/show?id=c818516291b' target=_blank style='color:#2F92EE;'>#心脏磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51629, encryptionId=c818516291b, topicName=心脏磁共振)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3f342339746, createdName=mhzhuang@stu.e, createdTime=Fri May 17 15:52:00 CST 2019, time=2019-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1447195, encodeId=613f144e19546, content=<a href='/topic/show?id=dd2f31009da' target=_blank style='color:#2F92EE;'>#冠脉造影#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31009, encryptionId=dd2f31009da, topicName=冠脉造影)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/g?b=oidb&k=l9h0OhA0BicNC4kpEUl4AeA&s=100&t=1587635346, createdBy=61865326685, createdName=李研东, createdTime=Fri May 17 15:52:00 CST 2019, time=2019-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1482251, encodeId=0517148225181, content=<a href='/topic/show?id=8cc416e78f3' target=_blank style='color:#2F92EE;'>#STEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16778, encryptionId=8cc416e78f3, topicName=STEM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d1067833268, createdName=12498bb3m92(暂无昵称), createdTime=Fri May 17 15:52:00 CST 2019, time=2019-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1494110, encodeId=f009149411059, content=<a href='/topic/show?id=3e34949e333' target=_blank style='color:#2F92EE;'>#造影#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94973, encryptionId=3e34949e333, topicName=造影)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=908d9134595, createdName=sodoo, createdTime=Fri May 17 15:52:00 CST 2019, time=2019-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1500931, encodeId=6110150093113, content=<a href='/topic/show?id=3cad13104d5' target=_blank style='color:#2F92EE;'>#NSTEMI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13104, encryptionId=3cad13104d5, topicName=NSTEMI)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Fri May 17 15:52:00 CST 2019, time=2019-05-17, status=1, ipAttribution=)]
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    2019-05-17 sodoo
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    2019-05-17 hb2008ye

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Crit Care:非ST段抬高型心肌梗死患者闭塞的犯罪动脉患病率和结局分析!

由此可见,大部分是NSTEMI人群为OCA患者。这些患者表现出更严重的症状和更差的临床结局。这些患者是否应该采取更积极的治疗策略还有待进一步研究。

JAHA:TCT大会期间,美国心梗患者死亡率较低,尤其是NSTEMI

近日哈佛医学院学者在美国心脏协会杂志(JAHA)刊登的一项研究表明,在美国经导管心血管治疗学术会议(TCT)期间,住院的急性心肌梗死患者30天死亡率较低,尤其是非ST段抬高型心梗(NSTEMI)死亡率有差别。