Plos One:肾损伤患者中使用胰岛素加葡萄糖治疗高钾血症后的低血糖发生情况

2017-03-01 MedSci MedSci原创

低血糖是在高钾血症施用胰岛素后的严重并发症。近期,一篇发表在杂志Plos One上的文章研究了静脉内输注胰岛素加葡萄糖治疗高钾血症的AKI和非透析CKD患者中的低血糖和严重低血糖(血糖分别为<70或≤40mg/ dl)的发生率。研究者们回顾性地分析了2013年12月1日至2015年5月31日接受10U胰岛素加50g葡萄糖治疗高钾血症的所有AKI和非透析CKD患者的资料。此项研究结果显示:共有

低血糖是在高钾血症施用胰岛素后的严重并发症。


近期,一篇发表在杂志Plos One上的文章研究了静脉内输注胰岛素加葡萄糖治疗高钾血症的AKI和非透析CKD患者中的低血糖和严重低血糖(血糖分别为<70或≤40mg/ dl)的发生率。

研究者们回顾性地分析了2013年12月1日至2015年5月31日接受10U胰岛素加50g葡萄糖治疗高钾血症的所有AKI和非透析CKD患者的资料。

此项研究结果显示:共有164次使用胰岛素加葡萄糖治疗高钾血症。血清钾水平下降了1.18±1.01 mmol / l。其中11个治疗(6.1%)导致低血糖,2个治疗(1.2%)导致严重低血糖。较低的预处理血糖与随后低血糖风险较高相关。年龄,性别,肾功能,糖尿病的确定诊断或此前的治疗与这种并发症的发展并不相关。

此项研究得出结论:静脉输注胰岛素加葡萄糖可以有效地降低血清钾水平,且与症状性低血糖和其他并发症的低风险有关。

原始出处:
Coca A, Valencia AL, et al. Hypoglycemia following intravenous insulin plus glucose for hyperkalemia in patients with impaired renal function. PLoS One. 2017 Feb 28;12(2):e0172961. doi: 10.1371/journal.pone.0172961. eCollection 2017.

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    2018-02-01 baoya
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    2017-04-17 jyzxjiangqin

    肾损伤患者使用胰岛素的情况。

    0

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    2017-04-04 jyzxjiangqin

    肾损伤患者中使用胰岛素加葡萄糖治疗情况。

    0

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    2017-03-03 zhaojie88
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    2017-03-02 1ddf0692m34(暂无匿称)

    胰岛素可促进钾进入细胞

    0

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