Curr Eye Res:急性低血容量对眼睛的影响

2018-04-09 cuiguizhong MedSci原创

土耳其伊斯坦布尔卡努尼苏丹苏莱曼教育和研究医院眼科的Araz-Ersan HB近日在Curr Eye Res发表了一篇文章,他们探讨了献血引起的急性血容量不足对眼部的影响。

土耳其伊斯坦布尔卡努尼苏丹苏莱曼教育和研究医院眼科的Araz-Ersan HB近日在Curr Eye Res发表了一篇文章,他们探讨了献血引起的急性血容量不足对眼部的影响。

这是一项前瞻性观察性研究,其研究对象为48名年龄在20至40岁之间的健康男性的其中一只眼睛,他们都捐献了500毫升血液;其对照组是年龄和性别匹配的28位健康男性的28只眼睛。在献血前和在献血后10分钟以及第1、2、3和4小时,测量眼部参数,包括眼部灌注压(OPP)、眼内压(IOP)、轴向长度(AL)、中央角膜厚度(CCT)、脉络膜和视网膜厚度以及视网膜神经纤维层(RNFL)。

结果他们发现,献血后平均OPP显着降低(基线43.4±4.9比40.8±4.6 mmHg; p = 0.003)。在献血前、基线标准,献血后10分钟和1、2、3和4小时,平均中心凹下脉络膜厚度(SFCT)分别为322.96±76.23, 291.63±77.85, 309.77±75.72, 312.31±75.98, 315.73±75.43和317.75±75.73μm [F(2.462,115.731)= 22.618,p <0.001]。对照组在基线,10分钟和1,2,3和4时测量的SFCT分别为302.04±32.04, 301.43±35.16, 298.07±37.33, 298.96±39.17, 302.54±39.24和301.61±40.41μm [F(2.124,57.340)= 0.592,p = 0.566]。在献血前后AL、CCT、RNFL、视网膜厚度和IOP没有显着性差异(p> 0.05)。

因此,他们认为,急性低血容量导致SFCT显着降低,大约持续3小时。本研究可能为更好地了解疾病状态下脉络膜厚度变化铺平道路。

原文出处:

Araz-Ersan, H.B., et al., The Effect of Acute Hypovolemia on the Eye. Curr Eye Res, 2018: p. 1-6.

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    2018-06-05 wrj0121
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    2018-04-10 张新亮1853311252142e2fm

    好文章学习了

    0

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    2018-04-09 zdvfsadb

    学习了

    0