Radiology:高龄急性缺血性脑卒中要不要介入治疗呢?

2018-08-07 shaosai MedSci原创

本研究旨在评价老龄缺血性急性脑卒中患者年龄对血管内治疗(EVT)联合常规护理效果的影响,将结果发表在radiology上。

本研究旨在评价老龄缺血性急性脑卒中患者年龄对血管内治疗(EVT)联合常规护理效果的影响,将结果发表在radiology上。

本研究利用决策-分析Markov模型评价直接和间接生存成分和质量相对寿命(QALYs)。通过文献得到年两相关输入指标。采用脑卒中索引决定性和可能性分析。意愿支付(WTP)阈值设定每QALY 为$50 000、$100 000、$150 000。通过决定性和可能性敏感性分析获取额外支付和受益。确定不同WTP阈值的可接受率。

结果为,EVT+SC是50-79岁急性脑卒中患者主要的治疗策略。在50岁的患者中有最高的额外受益(2.61 QALYs)和节省花费(医疗花费为$99 555; 社会活动花费为$146 385)。对于80-89岁的患者,EVT+SC治疗策略在增加花费的基础上能够获得额外受益,在WTP为每QALY $50 000、$100 000、$150 000下,接受率分别为85%、>99%、>99%;在90-99岁的患者,WTP为每QALY$50 000的接受率下降,但在WTP为每QALY $100 000、$150 000的接受率仍高于85% 、95%。

本研究表明,利用现在医院支付阈值,血管内治疗联合常规护理减少高于79岁患者的生存花费,对80-100岁的患者是一种高性价比的选择。

原始出处:

Kunz WG, Hunink MG, Dimitriadis K. et al.Cost-effectiveness of Endovascular Therapy for Acute Ischemic Stroke: A Systematic Review of the Impact of Patient Age.Radiology.DOI:10.1148/radiol.2018172886

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    2018-08-21 一一一多

    医疗成本

    0

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    2018-08-10 太阳系小猪

    也就是高领患者,介入治疗性价比比较高~

    0

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    2018-08-09 xlysu
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    2018-08-08 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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