Science:全球变暖将疟疾推向热带高海拔地区

2014-03-07 佚名 生物360

历史上,热带较高海拔地区的较为凉爽的气温为人们提供了一些免于感染疟原虫的庇护所,因为当气温低的时候,蚊媒难以完成其生命周期,而疟原虫的复制速度也会减慢。 然而,日前来自密歇根大学(University of Michigan)等机构的研究人员在《科学》(Sciecne)杂志上报告称,他们发现当较高海拔地区的气温升高时,在这些高度的疟疾病例会同步地变得 更为常见,尤其是在非洲及南美洲的高原地区,如

历史上,热带较高海拔地区的较为凉爽的气温为人们提供了一些免于感染疟原虫的庇护所,因为当气温低的时候,蚊媒难以完成其生命周期,而疟原虫的复制速度也会减慢。

然而,日前来自密歇根大学(University of Michigan)等机构的研究人员在《科学》(Sciecne)杂志上报告称,他们发现当较高海拔地区的气温升高时,在这些高度的疟疾病例会同步地变得 更为常见,尤其是在非洲及南美洲的高原地区,如果全球暖化趋势持续不减,这种情况可能会是疟疾蔓延至人口稠密的高原地区的一个重大问题。

因此,研究人员从哥伦比亚西部的 124 个不同的城市及埃塞俄比亚中部的 159 个行政单位采集了详细的时空数据。他们分析了疟疾病例的垂直分布并发现,确实,在较暖和的年份中,在较高海拔地区会有更多的疟疾病例报告。

此后,研究人员创建了一个能够说明诸如杀虫剂及抗虐药物使用等因素的模型,且该模型预测,如果情况没有得到缓解,温度只要上升 1 度,仅在这两个大陆上就会造成每年增加成千上万的疟疾感染病例。

原始出处:

A. S. Siraj, M. Santos-Vega, M. J. Bouma, D. Yadeta, D. Ruiz Carrascal, and M. Pascual. Altitudinal Changes in Malaria Incidence in Highlands of Ethiopia and Colombia. Science, 7 March 2014; DOI:10.1126/science.1244325

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2037643, encodeId=ac26203e6439f, content=<a href='/topic/show?id=3c2010246605' target=_blank style='color:#2F92EE;'>#高海拔地区#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102466, encryptionId=3c2010246605, topicName=高海拔地区)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/lGEyfsKnIkkH93xUPMrUUycLh2XOfJJsphwPsVqDx8somSOepIFy9QE0MVAwDW3AS7V1epJ4tbPL9ADJLicvm8A/132, createdBy=b5132500067, createdName=ms55066533437992, createdTime=Wed Jan 14 11:57:00 CST 2015, time=2015-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1688376, encodeId=c52216883e6f4, content=<a href='/topic/show?id=df81656161b' target=_blank style='color:#2F92EE;'>#海拔#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65616, encryptionId=df81656161b, topicName=海拔)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f1c128575901, createdName=12498974m60暂无昵称, createdTime=Sat Aug 16 06:57:00 CST 2014, time=2014-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1942162, encodeId=60af1942162e0, content=<a href='/topic/show?id=c489102465b4' target=_blank style='color:#2F92EE;'>#高海拔#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102465, encryptionId=c489102465b4, topicName=高海拔)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Fri Oct 17 20:57:00 CST 2014, time=2014-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1374844, encodeId=577513e484484, content=<a href='/topic/show?id=2949159989d' target=_blank style='color:#2F92EE;'>#SCIE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15998, encryptionId=2949159989d, topicName=SCIE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=17a3387, createdName=jichang, createdTime=Sun Mar 09 04:57:00 CST 2014, time=2014-03-09, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2037643, encodeId=ac26203e6439f, content=<a href='/topic/show?id=3c2010246605' target=_blank style='color:#2F92EE;'>#高海拔地区#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102466, encryptionId=3c2010246605, topicName=高海拔地区)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/lGEyfsKnIkkH93xUPMrUUycLh2XOfJJsphwPsVqDx8somSOepIFy9QE0MVAwDW3AS7V1epJ4tbPL9ADJLicvm8A/132, createdBy=b5132500067, createdName=ms55066533437992, createdTime=Wed Jan 14 11:57:00 CST 2015, time=2015-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1688376, encodeId=c52216883e6f4, content=<a href='/topic/show?id=df81656161b' target=_blank style='color:#2F92EE;'>#海拔#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65616, encryptionId=df81656161b, topicName=海拔)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f1c128575901, createdName=12498974m60暂无昵称, createdTime=Sat Aug 16 06:57:00 CST 2014, time=2014-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1942162, encodeId=60af1942162e0, content=<a href='/topic/show?id=c489102465b4' target=_blank style='color:#2F92EE;'>#高海拔#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102465, encryptionId=c489102465b4, topicName=高海拔)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Fri Oct 17 20:57:00 CST 2014, time=2014-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1374844, encodeId=577513e484484, content=<a href='/topic/show?id=2949159989d' target=_blank style='color:#2F92EE;'>#SCIE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15998, encryptionId=2949159989d, topicName=SCIE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=17a3387, createdName=jichang, createdTime=Sun Mar 09 04:57:00 CST 2014, time=2014-03-09, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2037643, encodeId=ac26203e6439f, content=<a href='/topic/show?id=3c2010246605' target=_blank style='color:#2F92EE;'>#高海拔地区#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102466, encryptionId=3c2010246605, topicName=高海拔地区)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/lGEyfsKnIkkH93xUPMrUUycLh2XOfJJsphwPsVqDx8somSOepIFy9QE0MVAwDW3AS7V1epJ4tbPL9ADJLicvm8A/132, createdBy=b5132500067, createdName=ms55066533437992, createdTime=Wed Jan 14 11:57:00 CST 2015, time=2015-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1688376, encodeId=c52216883e6f4, content=<a href='/topic/show?id=df81656161b' target=_blank style='color:#2F92EE;'>#海拔#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65616, encryptionId=df81656161b, topicName=海拔)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f1c128575901, createdName=12498974m60暂无昵称, createdTime=Sat Aug 16 06:57:00 CST 2014, time=2014-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1942162, encodeId=60af1942162e0, content=<a href='/topic/show?id=c489102465b4' target=_blank style='color:#2F92EE;'>#高海拔#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102465, encryptionId=c489102465b4, topicName=高海拔)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Fri Oct 17 20:57:00 CST 2014, time=2014-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1374844, encodeId=577513e484484, content=<a href='/topic/show?id=2949159989d' target=_blank style='color:#2F92EE;'>#SCIE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15998, encryptionId=2949159989d, topicName=SCIE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=17a3387, createdName=jichang, createdTime=Sun Mar 09 04:57:00 CST 2014, time=2014-03-09, status=1, ipAttribution=)]
    2014-10-17 zsyan
  4. [GetPortalCommentsPageByObjectIdResponse(id=2037643, encodeId=ac26203e6439f, content=<a href='/topic/show?id=3c2010246605' target=_blank style='color:#2F92EE;'>#高海拔地区#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102466, encryptionId=3c2010246605, topicName=高海拔地区)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/lGEyfsKnIkkH93xUPMrUUycLh2XOfJJsphwPsVqDx8somSOepIFy9QE0MVAwDW3AS7V1epJ4tbPL9ADJLicvm8A/132, createdBy=b5132500067, createdName=ms55066533437992, createdTime=Wed Jan 14 11:57:00 CST 2015, time=2015-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1688376, encodeId=c52216883e6f4, content=<a href='/topic/show?id=df81656161b' target=_blank style='color:#2F92EE;'>#海拔#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65616, encryptionId=df81656161b, topicName=海拔)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f1c128575901, createdName=12498974m60暂无昵称, createdTime=Sat Aug 16 06:57:00 CST 2014, time=2014-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1942162, encodeId=60af1942162e0, content=<a href='/topic/show?id=c489102465b4' target=_blank style='color:#2F92EE;'>#高海拔#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102465, encryptionId=c489102465b4, topicName=高海拔)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Fri Oct 17 20:57:00 CST 2014, time=2014-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1374844, encodeId=577513e484484, content=<a href='/topic/show?id=2949159989d' target=_blank style='color:#2F92EE;'>#SCIE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15998, encryptionId=2949159989d, topicName=SCIE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=17a3387, createdName=jichang, createdTime=Sun Mar 09 04:57:00 CST 2014, time=2014-03-09, status=1, ipAttribution=)]
    2014-03-09 jichang

相关资讯

J Infect Dis:无胎盘疟疾的初产妇诞下的婴儿患疟疾风险较低

     初产妇和经产妇在有或无胎盘疟疾情况下其婴儿患寄生虫血症或临床型疟疾的风险 妊娠期疟疾导致母体贫血以及不好的妊娠结果,如流产、早产或低体重初生儿。据统计,每年大约有75000-200000的婴儿因妊娠期疟疾而死亡。与经产妇相比,初产妇患胎盘疟疾风险较高,妊娠结果不好的可能性也较大。在非洲,妊娠期疟疾与婴儿疟疾发病率的升高相关。然而,很少有研究致力于探索胎盘疟疾对不同妊娠次数妇女产下的婴

Science:里程碑!科学家成功研制安全高效的疟疾疫苗

疟疾是一种威胁生命的疾病,世界卫生组织在 2010 年估计每天这种疾病会造成 2000 人死亡,且长期以来一直缺乏高效的疫苗,但现在,研究人员正在这一领域取得进展。 尽管他们制造的疫苗仅能通过静脉给予(而不是更为常见的通过肌肉内、皮内或鼻腔内通路给予),但它的确为广泛适用的疟疾预防铺平了道路。【原文下载】 有很大数目的疟疾病例是由恶性疟原虫(Pf)引起的,这是通过蚊虫叮咬而传播给人的寄生虫

PNAS:科学家揭示气候改变引发的全球疟疾分布情况

近日,刊登在国际杂志PNAS上的一篇研究论文中,来自利物浦大学的研究人员通过研究表示,由于气候变化的影响在本世纪末疟疾将会在高低地区被越来越多地出现。 文章中,研究者表示,截止21世纪80年代,在东非将会有1亿人暴露于疟疾感染之中,而由于气候变化所引发的疟疾流行的机制目前并不清楚,Cyril Caminade博士表示,利用我们开发的新型统计学模型就可以对疾病爆发的情形进行有效的预测。 2010

Nature:对青蒿素有抗药性的疟疾的一个标记

青蒿素抗药性在所分离出的东南亚疟疾病原体“镰刀形疟原虫”中的传播,可能会葬送为在全世界根除这种疾病所做努力。监测抗药性这一重要工作一直受阻于缺少一个分子标记。 现在,Frédéric Ariey及同事识别出了“镰刀形疟原虫”青蒿素抗药性的一个主要决定因子,它也许能提供这样一个标记。他们发现,该寄生虫的PF3D7_1343700 kelch propeller domain (K-13 prope

Nature Comm:疟疾的疟原虫喜欢年轻的血细胞

人类更多地接触猕猴疟原虫“诺氏疟原虫”,可能会导致其入侵较老血细胞的能力增强。由于这些寄生虫目前喜欢较年轻的血细胞,所以发表在Nature Communications上的这项研究表明,“诺氏疟原虫”在人体中的毒性及其传播能力今后可能会增强。 Caeul Lim及其同事报告说,“诺氏疟原虫”在人血中生长状况差是由于它喜欢入侵一个年轻亚类的细胞。他们发现,连续接触人血导致该寄生虫的演化及其感染更大

第六届多边倡议泛非疟疾会议 2013 :“不完美”疟疾疫苗走向市场

                   即使是略微有效的疟疾疫苗也可以减少很多由疟疾产生的住院病例。    图片来源:Adriane Ohanesian/Reuters 完美与好不应该是敌人,特别是在对抗像疟疾这样的毁灭性疾病时更是如此。一种新的疫苗正在迅速进入疟疾药物的市场,在接种该疫苗的大龄儿童中,有不到一半的孩子实现了成功预防。 从2009年3月起研究人员就开