并购复苏!渤健、uniQure、AZ等谁是大型药企下一个目标?

2019-06-27 newborn 新浪医药新闻

6月25日晚间,艾伯维与艾尔建联合宣布,双方已签订一项最终交易协议,艾伯维将以现金加股票交易方式收购艾尔建,交易总价约630亿美元,对应每股188.24美元,较艾尔建周一收盘价溢价45%。

6月25日晚间,艾伯维与艾尔建联合宣布,双方已签订一项最终交易协议,艾伯维将以现金加股票交易方式收购艾尔建,交易总价约630亿美元,对应每股188.24美元,较艾尔建周一收盘价溢价45%。

对于此次收购,艾伯维认为,该笔交易有助于两家公司实现转型,并且可以获得独特和互补的战略目标。不过,艾伯维的投资者对这笔交易并不满意,消息公布后,公司股价盘前下跌超10%,市值蒸发180亿美元,而艾尔建股价则上涨30%。

针对生物制药领域未来的并购活动,加拿大皇家资本市场(RBC Capital Markets)迅速开展了一项调查,并将其发送给客户,要求其预测该领域并购活动是否能保持强劲,如果是,哪些公司最有可能成为首要目标。

RBC分析师周三发给投资者的一份报告中得出结论:生物制药行业在今年下半年并购活动将继续保持强劲,但关于并购目标名单却众说纷纭。

根据报告,荷兰基因治疗公司uniQure是多数调查对象认为的并购目标,该公司是基因治疗领域的先驱,曾为了在欧洲销售其“一针百万”的基因疗法Glybera而苦苦挣扎,以至于在2017年上市期限到期时拒绝更新营销授权,最终这款在西方世界艰难问世的首款基因疗法黯然退市。但随后该公司又转头将一款治疗血友病的基因疗法推进了III期临床

上周,有报道称,uniQure正在权衡出售或合作。有分析师认为,诺和诺德、辉瑞、赛诺菲是最有可能的收购方,但必须拿出足够的资金,因为在今年以来,uniQure股价已暴涨160%以上。

艾伯维和艾尔建的“联姻”是今年生物制药领域并购复苏的最新证据。去年12月,GSK 50亿美元收购肿瘤学公司Tesaro,首次暗示2019年将是达成交易的重要一年。之后,BMS 740亿美元收购新基,礼来80亿美元收购了Loxo Oncology。目前,罗氏正以40亿美元收购Spark Therapeutics,辉瑞计划以140亿美元收购Array BioPharma。

几家规模不等的公司被RBC受访者列入下一个最有可能的收购目标,其中大型生物制药公司中首推的是阿斯利康和渤健,而小型生物制药公司中首推的是BioHaven、Blueprint Medicines、The Medicines Company。

渤健出现在榜单上并不奇怪。今年早些时候,aducanumab治疗阿尔茨海默氏症III期临床失败后,就有华尔街分析师预测,该公司要么需要展开一笔重大交易来支撑管线,要么面临被收购的风险。自3月宣布aducanumab失败以来,渤健股价已经下跌超过25%,彭博社也在最近的一篇报道中指出,渤健被列为了TOP收购目标。

在支撑管线方面,渤健也确实做了一些工作。今年3月,以8.77亿美元收购了基因治疗公司Nightstar Therapeutics,但大多数分析师认为,鉴于其畅销多发性硬化症药物Tecfidera正面临专利挑战,此次收购并不能带来多少改观。

RBC分析师指出,2019年余下时间,生物制药行业的情绪“将受到并购活动的推动”,尽管“预测重大交易仍将困难,但考虑到有利的估值,多数交易将是收购规模较小的、处于早期阶段的生物制药公司。”

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1796589, encodeId=0aff1e9658909, content=<a href='/topic/show?id=ded018138d8' target=_blank style='color:#2F92EE;'>#uniQure#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18138, encryptionId=ded018138d8, topicName=uniQure)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=32a12500167, createdName=12498ca5m83暂无昵称, createdTime=Mon Feb 17 13:48:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1305481, encodeId=64bc13054819a, content=<a href='/topic/show?id=270342e249d' target=_blank style='color:#2F92EE;'>#复苏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42724, encryptionId=270342e249d, topicName=复苏)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1d01326, createdName=lizhou0204, createdTime=Sat Jun 29 12:48:00 CST 2019, time=2019-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1468807, encodeId=62d9146880edb, content=<a href='/topic/show?id=ce0049043f3' target=_blank style='color:#2F92EE;'>#并购#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49043, encryptionId=ce0049043f3, topicName=并购)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6fbc6938060, createdName=canlab, createdTime=Sat Jun 29 12:48:00 CST 2019, time=2019-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=368511, encodeId=5c543685112f, content=666, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/01/04/2540fb84decb81d47a7f2868070e6cbd.jpg, createdBy=ed3f2205793, createdName=百草, createdTime=Fri Jun 28 07:36:50 CST 2019, time=2019-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1714837, encodeId=1be91e14837e5, content=<a href='/topic/show?id=021230e312' target=_blank style='color:#2F92EE;'>#AZ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3073, encryptionId=021230e312, topicName=AZ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5031899089, createdName=12498e5fm22(暂无昵称), createdTime=Sun Jan 19 17:48:00 CST 2020, time=2020-01-19, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1796589, encodeId=0aff1e9658909, content=<a href='/topic/show?id=ded018138d8' target=_blank style='color:#2F92EE;'>#uniQure#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18138, encryptionId=ded018138d8, topicName=uniQure)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=32a12500167, createdName=12498ca5m83暂无昵称, createdTime=Mon Feb 17 13:48:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1305481, encodeId=64bc13054819a, content=<a href='/topic/show?id=270342e249d' target=_blank style='color:#2F92EE;'>#复苏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42724, encryptionId=270342e249d, topicName=复苏)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1d01326, createdName=lizhou0204, createdTime=Sat Jun 29 12:48:00 CST 2019, time=2019-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1468807, encodeId=62d9146880edb, content=<a href='/topic/show?id=ce0049043f3' target=_blank style='color:#2F92EE;'>#并购#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49043, encryptionId=ce0049043f3, topicName=并购)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6fbc6938060, createdName=canlab, createdTime=Sat Jun 29 12:48:00 CST 2019, time=2019-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=368511, encodeId=5c543685112f, content=666, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/01/04/2540fb84decb81d47a7f2868070e6cbd.jpg, createdBy=ed3f2205793, createdName=百草, createdTime=Fri Jun 28 07:36:50 CST 2019, time=2019-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1714837, encodeId=1be91e14837e5, content=<a href='/topic/show?id=021230e312' target=_blank style='color:#2F92EE;'>#AZ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3073, encryptionId=021230e312, topicName=AZ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5031899089, createdName=12498e5fm22(暂无昵称), createdTime=Sun Jan 19 17:48:00 CST 2020, time=2020-01-19, status=1, ipAttribution=)]
    2019-06-29 lizhou0204
  3. [GetPortalCommentsPageByObjectIdResponse(id=1796589, encodeId=0aff1e9658909, content=<a href='/topic/show?id=ded018138d8' target=_blank style='color:#2F92EE;'>#uniQure#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18138, encryptionId=ded018138d8, topicName=uniQure)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=32a12500167, createdName=12498ca5m83暂无昵称, createdTime=Mon Feb 17 13:48:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1305481, encodeId=64bc13054819a, content=<a href='/topic/show?id=270342e249d' target=_blank style='color:#2F92EE;'>#复苏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42724, encryptionId=270342e249d, topicName=复苏)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1d01326, createdName=lizhou0204, createdTime=Sat Jun 29 12:48:00 CST 2019, time=2019-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1468807, encodeId=62d9146880edb, content=<a href='/topic/show?id=ce0049043f3' target=_blank style='color:#2F92EE;'>#并购#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49043, encryptionId=ce0049043f3, topicName=并购)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6fbc6938060, createdName=canlab, createdTime=Sat Jun 29 12:48:00 CST 2019, time=2019-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=368511, encodeId=5c543685112f, content=666, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/01/04/2540fb84decb81d47a7f2868070e6cbd.jpg, createdBy=ed3f2205793, createdName=百草, createdTime=Fri Jun 28 07:36:50 CST 2019, time=2019-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1714837, encodeId=1be91e14837e5, content=<a href='/topic/show?id=021230e312' target=_blank style='color:#2F92EE;'>#AZ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3073, encryptionId=021230e312, topicName=AZ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5031899089, createdName=12498e5fm22(暂无昵称), createdTime=Sun Jan 19 17:48:00 CST 2020, time=2020-01-19, status=1, ipAttribution=)]
    2019-06-29 canlab
  4. [GetPortalCommentsPageByObjectIdResponse(id=1796589, encodeId=0aff1e9658909, content=<a href='/topic/show?id=ded018138d8' target=_blank style='color:#2F92EE;'>#uniQure#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18138, encryptionId=ded018138d8, topicName=uniQure)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=32a12500167, createdName=12498ca5m83暂无昵称, createdTime=Mon Feb 17 13:48:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1305481, encodeId=64bc13054819a, content=<a href='/topic/show?id=270342e249d' target=_blank style='color:#2F92EE;'>#复苏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42724, encryptionId=270342e249d, topicName=复苏)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1d01326, createdName=lizhou0204, createdTime=Sat Jun 29 12:48:00 CST 2019, time=2019-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1468807, encodeId=62d9146880edb, content=<a href='/topic/show?id=ce0049043f3' target=_blank style='color:#2F92EE;'>#并购#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49043, encryptionId=ce0049043f3, topicName=并购)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6fbc6938060, createdName=canlab, createdTime=Sat Jun 29 12:48:00 CST 2019, time=2019-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=368511, encodeId=5c543685112f, content=666, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/01/04/2540fb84decb81d47a7f2868070e6cbd.jpg, createdBy=ed3f2205793, createdName=百草, createdTime=Fri Jun 28 07:36:50 CST 2019, time=2019-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1714837, encodeId=1be91e14837e5, content=<a href='/topic/show?id=021230e312' target=_blank style='color:#2F92EE;'>#AZ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3073, encryptionId=021230e312, topicName=AZ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5031899089, createdName=12498e5fm22(暂无昵称), createdTime=Sun Jan 19 17:48:00 CST 2020, time=2020-01-19, status=1, ipAttribution=)]
    2019-06-28 百草

    666

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1796589, encodeId=0aff1e9658909, content=<a href='/topic/show?id=ded018138d8' target=_blank style='color:#2F92EE;'>#uniQure#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18138, encryptionId=ded018138d8, topicName=uniQure)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=32a12500167, createdName=12498ca5m83暂无昵称, createdTime=Mon Feb 17 13:48:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1305481, encodeId=64bc13054819a, content=<a href='/topic/show?id=270342e249d' target=_blank style='color:#2F92EE;'>#复苏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42724, encryptionId=270342e249d, topicName=复苏)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1d01326, createdName=lizhou0204, createdTime=Sat Jun 29 12:48:00 CST 2019, time=2019-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1468807, encodeId=62d9146880edb, content=<a href='/topic/show?id=ce0049043f3' target=_blank style='color:#2F92EE;'>#并购#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49043, encryptionId=ce0049043f3, topicName=并购)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6fbc6938060, createdName=canlab, createdTime=Sat Jun 29 12:48:00 CST 2019, time=2019-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=368511, encodeId=5c543685112f, content=666, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/01/04/2540fb84decb81d47a7f2868070e6cbd.jpg, createdBy=ed3f2205793, createdName=百草, createdTime=Fri Jun 28 07:36:50 CST 2019, time=2019-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1714837, encodeId=1be91e14837e5, content=<a href='/topic/show?id=021230e312' target=_blank style='color:#2F92EE;'>#AZ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3073, encryptionId=021230e312, topicName=AZ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5031899089, createdName=12498e5fm22(暂无昵称), createdTime=Sun Jan 19 17:48:00 CST 2020, time=2020-01-19, status=1, ipAttribution=)]