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糖尿病相关GWAS检测项目(DIAGRAM)的原始数据资料

2019-10-10 MedSci 网络

糖尿病GWAS
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Stage 1 GWAS: Summary Statistics Please note that the summary statistics presented in this file have NOT been corrected for a second round of genomic control after meta-analysis.

Stage 1 GWAS: Summary Statistics

Please note that the summary statistics presented in this file have NOT been corrected for a second round of genomic control after meta-analysis. However the P values in the Morris et al paper WERE double GC corrected. There are more details in the PDF below.

The data is made available as a tab-separated table, enclosed in a zip file (about 32Mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

  • not to attempt to de-identify individual subjects.
  •  

SHA1:cc76628428531d978d5aadb5d9e5b73cd0b4cbbe, MD5:b39b008322c22c8fa80a029738cd1155.

Stage 1 GWAS & Stage 2 Metabochip: Summary Statistics

The data is made available as a tab-separated table, enclosed in a zip file (about 3.3Mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

  • not to attempt to de-identify individual subjects.
  •  

SHA1:4e9353d1c8e6399bc3abb6c9fa9bf76d4463c5f7, MD5:7a53d81e4e70e180fc0ca2b243aaeb69.

Stage 1 GWAS & Stage 2 Metabochip: Sex-Specific Summary Statistics

The data is made available as a tab-separated table, enclosed in a zip file (about 7Mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

  • not to attempt to de-identify individual subjects.
  •  

SHA1:8bf2679a087f5418b05a92c3b04a2b2aebcdc82a, MD5:e182d0908085be895b6cb7a066c3198d.

Stage 2 Metabochip: Summary Statistics

The data is made available as a tab-separated table, enclosed in a zip file (about 3.5Mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

  • not to attempt to de-identify individual subjects.
  •  

SHA1:ff90a898d682c7899aba0fa965eb82116e0bb25e, MD5:c59b327be3dcf3b162fc70d8994bc3e1.

Trans-ethnic T2D GWAS meta-analysis

The data is made available as a tab-separated table, enclosed in a zip file (about 46Mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

  • not to attempt to de-identify individual subjects.
  •  

SHA1:md1563f04bf552510953baa62c5dc549b33465096a, MD5:bb41de5f92fc3f62527b64062e2aa0f5.

DIAGRAM Metabochip meta-analysis of T2D: Summary Statistics

Published in Gaulton et al., Nature Genetics, 2015

The data is made available as a tab-separated table, enclosed in a zip file (less than 1Mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

  • not to attempt to de-identify individual subjects.
  •  

SHA1:213f12b6b3fce14e85cb42fbe820e6cf135f6749, MD5:0f75aaf921e97b2fea991bd90c1ca60b.

DIAGRAM Metabochip meta-analysis of T2D: Credible Sets

Published in Gaulton et al., Nature Genetics, 2015

The data is made available as a collection of tab-separated tables, enclosed in a zip file (less than 400Kb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

  • not to attempt to de-identify individual subjects.
  •  

SHA1:902a4c1c4b9aca49d84b536accd1dd6b7395aa2b, MD5:db32d3e6853ad318f440e90f7f4058de.

GoT2D and T2D-GENES meta-analysis of T2D: Summary Statistics

Published in Fuchsberger  et  al (2016)

The data is made available as a tab-separated table enclosed in a zip file (around 145mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

  • not to attempt to de-identify individual subjects.
  •  

SHA1:dfbed9c306b4f11c803b765887b2badaf8f3918a, MD5:1e76dbdf8f0291898332713cf001bc5a.

DIAGRAM 1000G GWAS meta-analysis Stage 1 Summary statistics

Published in in Scott et al (2017)

The data is made available as a tab-separated table enclosed in a zip file (around 155 mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

  • not to attempt to de-identify individual subjects.
  •  

SHA1:d48402f1ce501ea5b98335e6e15173bb865bb6f1, MD5:f033ebb95e01afedde7365e4fc6565a2.

DIAGRAM 1000G GWAS meta-analysis with adjustment for BMI Stage 1 Summary statistics

Published in in Scott et al (2017)

The data is made available as a tab-separated table enclosed in a zip file (around 138 mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

  • not to attempt to de-identify individual subjects.
  •  

SHA1:73d085832e7c768533fc95f3212e80b82ae4f4bd, MD5:a5e469b5cae0f98bbddac85491a2bfbd.

T2D ExomeChip meta-analysis - European Summary Statistics

Published in in Mahajan et al (2018a)

The data is made available as a tab-separated table enclosed in a zip file (around 6 mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

  • not to attempt to de-identify individual subjects.
  •  

SHA1:5c6f457fb9b089d92d4f90f7fe864f187fdd9c1d, MD5:58b5f6a4ef0e62ac938938c56bb64b17.

T2D ExomeChip meta-analysis - Trans-Ethnic Summary Statistics

Published in in Mahajan et al (2018a)

The data is made available as a tab-separated table enclosed in a zip file (around 9 mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

  • not to attempt to de-identify individual subjects.
  •  

SHA1:9c1a8dd30599cf38742c64178fbf8dba88cb6ef5, MD5:1506a74af688f032016322e0cc0f59e6.

T2D GWAS meta-analysis - Genetic Credible Sets

Published in in Mahajan et al (2018b)

The data is made available as a tab-separated table enclosed in a zip file (around 751K). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

  • not to attempt to de-identify individual subjects.
  •  

SHA1:a9d633e754a4427e102b99f151249bc49188a94e, MD5:0602214b6e50f4aad4cdd0e26eca9613.

T2D GWAS meta-analysis - Functional Credible Sets

Published in in Mahajan et al (2018b)

The data is made available as a tab-separated table enclosed in a zip file (around 488K). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

  • not to attempt to de-identify individual subjects.
  •  

SHA1:f108d9c62472d1273f9241b2154becf132c61b6d, MD5:8a10a7a0ca6c59cce1546490fd8bf2a4.

T2D GWAS meta-analysis - Unadjusted for BMI

Published in in Mahajan et al (2018b)

The data is made available as a tab-separated table enclosed in a zip file (around 347mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

  • not to attempt to de-identify individual subjects.
  •  

SHA1:112e0e789179e15049649151163f5a517ff3ed7e, MD5:53855134fd0862c402cf49ab6233ed6d.

T2D GWAS meta-analysis - Adjusted for BMI

Published in in Mahajan et al (2018b)

The data is made available as a tab-separated table enclosed in a zip file (around 314mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

  • not to attempt to de-identify individual subjects.
  •  

SHA1:10d50afe3a9df56a8a0f314b27f8db6db58189d3, MD5:a0855aa81bfe37456660d93819c196db.

T2D GWAS meta-analysis - Summary of T2D associations of HRC variants for only European UK Biobank subjects

Published in in Mahajan et al (2018b)

The data is made available as a tab-separated table enclosed in a zip file (around 164mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

  • not to attempt to de-identify individual subjects.
  •  

SHA1:59cd6aae76fce25edd01c0c06c42b3f36a65402e, MD5:dc15e7222f5f1f8ee0b937cd1ba53590.

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1639237, encodeId=d6c3163923ecc, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Jul 15 09:28:00 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1280045, encodeId=d2a6128004595, content=<a href='/topic/show?id=b05983454a' target=_blank style='color:#2F92EE;'>#GWAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8345, encryptionId=b05983454a, topicName=GWAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Fri Oct 11 17:28:00 CST 2019, time=2019-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=373721, encodeId=cc6e3e372111, content=好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Oct 10 05:50:38 CST 2019, time=2019-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1042759, encodeId=8de81042e591d, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Thu Oct 10 05:28:00 CST 2019, time=2019-10-10, status=1, ipAttribution=)]
    2020-07-15 ms9608593228839890

    #DIA#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1639237, encodeId=d6c3163923ecc, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Jul 15 09:28:00 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1280045, encodeId=d2a6128004595, content=<a href='/topic/show?id=b05983454a' target=_blank style='color:#2F92EE;'>#GWAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8345, encryptionId=b05983454a, topicName=GWAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Fri Oct 11 17:28:00 CST 2019, time=2019-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=373721, encodeId=cc6e3e372111, content=好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Oct 10 05:50:38 CST 2019, time=2019-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1042759, encodeId=8de81042e591d, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Thu Oct 10 05:28:00 CST 2019, time=2019-10-10, status=1, ipAttribution=)]
    2019-10-11 lxg951

    #GWAS#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1639237, encodeId=d6c3163923ecc, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Jul 15 09:28:00 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1280045, encodeId=d2a6128004595, content=<a href='/topic/show?id=b05983454a' target=_blank style='color:#2F92EE;'>#GWAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8345, encryptionId=b05983454a, topicName=GWAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Fri Oct 11 17:28:00 CST 2019, time=2019-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=373721, encodeId=cc6e3e372111, content=好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Oct 10 05:50:38 CST 2019, time=2019-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1042759, encodeId=8de81042e591d, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Thu Oct 10 05:28:00 CST 2019, time=2019-10-10, status=1, ipAttribution=)]
    2019-10-10 yjs木玉

    好好好好好好

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1639237, encodeId=d6c3163923ecc, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Jul 15 09:28:00 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1280045, encodeId=d2a6128004595, content=<a href='/topic/show?id=b05983454a' target=_blank style='color:#2F92EE;'>#GWAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8345, encryptionId=b05983454a, topicName=GWAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Fri Oct 11 17:28:00 CST 2019, time=2019-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=373721, encodeId=cc6e3e372111, content=好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Oct 10 05:50:38 CST 2019, time=2019-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1042759, encodeId=8de81042e591d, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Thu Oct 10 05:28:00 CST 2019, time=2019-10-10, status=1, ipAttribution=)]
    2019-10-10 misszhang

    谢谢MedSci提供最新的资讯

    0

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