Heart:多排螺旋CT灌注成像定量检测心肌灌注异常

2012-02-04 MedSci MedSci原创

  日本学者的一项研究表明,在急性心肌梗死(AMI)患者中,利用重叠合法分析的多排螺旋CT(MDCT)灌注成像可定量检测心肌灌注异常。论文于2012年1月27日在线发表于《心脏》(Heart)。   此项研究共纳入15例冠脉正常的对照者和26例行再灌注治疗后的AMI患者。利用MDCT对患者进行心脏灌注显像(MPI)。灌注参数包括组织血流量(TBF)、组织血容量(TBV)和平均通过时间(MTT)。

  日本学者的一项研究表明,在急性心肌梗死(AMI)患者中,利用重叠合法分析的多排螺旋CT(MDCT)灌注成像可定量检测心肌灌注异常。论文于2012年1月27日在线发表于《心脏》(Heart)。

  此项研究共纳入15例冠脉正常的对照者和26例行再灌注治疗后的AMI患者。利用MDCT对患者进行心脏灌注显像(MPI)。灌注参数包括组织血流量(TBF)、组织血容量(TBV)和平均通过时间(MTT)。记录血管造影和单电子发射计算机断层摄影(SPECT)相关数据。在10例受试者中对MPI数据与来自于心肌磁共振(MR)的数据进行对比。

  结果显示,梗死心肌的TBF和TBV显著低于非梗死区(P<0.01)。梗死区的MTT与非梗死区无显著差异。TBV彩图所示的缺损区与肌酸激酶峰值水平、QRS评分和SPECT缺损评分显著相关。在侧支循环良好的梗死心肌中,心内膜侧贲门上部的TBF或TBV比率显著高于侧支循环不佳和无侧支循环心肌(P<0.01)。线性回归分析显示CT和MR-MPI的TBF指标具有良好的一致性。

  链接:

  Quantitative myocardial perfusion analysis using multi-row detector CT in acute myocardial infarction

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    2012-02-05 zhaojie88
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    2012-02-05 slcumt