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澳大利亚TGA批准ILUMYA（tildrakizumab）用于治疗中重度斑块状银屑病

2018-09-23 MedSci MedSci原创

tildrakizumab澳大利亚银屑病
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Sun制药公司22日宣布，澳大利亚治疗用品管理局（TGA）已经批准其ILUMYATM（tildrakizumab）用于治疗患有中度至重度斑块状银屑病的成人。

Sun制药公司22日宣布，澳大利亚治疗用品管理局（TGA）已经批准其ILUMYATM（tildrakizumab）用于治疗患有中度至重度斑块状银屑病的成人。银屑病是一种慢性皮肤疾病，主要特征是在身上出现一块一块异常的皮肤。通常，这些块状皮肤异常会发红、发痒以及脱屑。

ILUMYATM能够选择性地结合IL-23的p19亚基并抑制其与IL-23受体的相互作用，进而抑制促炎细胞因子和趋化因子的释放。ILUMYATM在第0周和第4周完成初始剂量后每12周通过皮下注射一次。对于先前对tildrakizumab中的任何赋形剂具有严重超敏反应的患者，ILUMYATM是禁忌使用的，特别在包括活动性肺结核在内的临床感染的患者中禁忌使用。

Sun制药公司的西欧和澳大利亚业务负责人Hellen De Kloet说：“我们很高兴ILUMYATM能够获得此批准，我们正在启动一项患者支持计划，以帮助急需ILUMYATM的患者”。ILUMYATM是Sun制药的主要产品之一，并于2018年3月获得美国FDA批准，2018年9月获得欧盟EMA批准。


原始出处：

http://www.firstwordpharma.com/explore/trending#axzz5RuSmLB5m

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    2018-10-07 docwu2019

    #ILD#

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    2019-02-23 snf701207

    #mAb#

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    2018-09-25 gous

    #斑块状银屑病#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1661996, encodeId=6ca21661996be, content=<a href='/topic/show?id=260c9e210e' target=_blank style='color:#2F92EE;'>#ILD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9721, encryptionId=260c9e210e, topicName=ILD)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Sun Oct 07 13:38:00 CST 2018, time=2018-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1912036, encodeId=d14d1912036b8, content=<a href='/topic/show?id=4de7112046c' target=_blank style='color:#2F92EE;'>#mAb#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11204, encryptionId=4de7112046c, topicName=mAb)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25e7304, createdName=snf701207, createdTime=Sat Feb 23 00:38:00 CST 2019, time=2019-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1330097, encodeId=df03133009eb6, content=<a href='/topic/show?id=a91c5e92328' target=_blank style='color:#2F92EE;'>#斑块#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57923, encryptionId=a91c5e92328, topicName=斑块)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/4E6244DB7C1860858424437821E08291/100, createdBy=a6a52500039, createdName=ms3994565386320060, createdTime=Tue Sep 25 08:38:00 CST 2018, time=2018-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341119, encodeId=64b2134111966, content=<a href='/topic/show?id=b97e223562' target=_blank style='color:#2F92EE;'>#AKI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2235, encryptionId=b97e223562, topicName=AKI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f7482500171, createdName=ms4468361851264128, createdTime=Tue Sep 25 08:38:00 CST 2018, time=2018-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1449591, encodeId=dac5144959167, content=<a href='/topic/show?id=446f5e934a9' target=_blank style='color:#2F92EE;'>#斑块状银屑病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57934, encryptionId=446f5e934a9, topicName=斑块状银屑病)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=1ecb5492626, createdName=gous, createdTime=Tue Sep 25 08:38:00 CST 2018, time=2018-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483955, encodeId=f5c514839558b, content=<a href='/topic/show?id=66a666e3784' target=_blank style='color:#2F92EE;'>#澳大利亚#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66737, encryptionId=66a666e3784, topicName=澳大利亚)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=33da7929339, createdName=12498cbcm02(暂无昵称), createdTime=Tue Sep 25 08:38:00 CST 2018, time=2018-09-25, status=1, ipAttribution=)]
    2018-09-25 12498cbcm02(暂无昵称)

    #澳大利亚#

    0

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