Cell Metab:针对胰高血糖素通路治疗糖尿病

2012-04-16 Beyond 生物谷

胰岛素用于维持血液中糖在适当水平,胰岛素能清除血糖,也称为胰高血糖素。   理查德·联合在医学部的教授和研究副主席艾拉塔巴斯博士说,我们发现一种方式以减少胰高血糖素对血糖的影响,并且不带来无副作用。   在过去十年中,由于肠促胰岛素的成功,带来了有关II型糖尿病药物的胰高血糖素研究的复兴。肠促胰岛素刺激胰岛素的分泌,但最近的研究表明,肠促胰岛素的临床成功可以归结为抑制胰

胰岛素用于维持血液中糖在适当水平,胰岛素能清除血糖,也称为胰高血糖素。

 

理查德·联合在医学部的教授和研究副主席艾拉塔巴斯博士说,我们发现一种方式以减少胰高血糖素对血糖的影响,并且不带来无副作用。

 

在过去十年中,由于肠促胰岛素的成功,带来了有关II型糖尿病药物的胰高血糖素研究的复兴。肠促胰岛素刺激胰岛素的分泌,但最近的研究表明,肠促胰岛素的临床成功可以归结为抑制胰高血糖素分泌。

 

 

Tabas博士发现,一旦胰高血糖素与其受体结合,CaMKII被激活后,葡萄糖被完全释放出来。CaMKII的激活时,一种蛋白质称为FoxO1本文系梅斯医学(MedSci)原创编译整理,转载需授权!-->

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    2012-06-13 guojianrong
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    2012-12-03 一闲
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    2013-02-22 维他命
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