JACC:不容忽视的自发性冠脉夹层

2017-08-24 MedSci MedSci原创

自发性冠脉夹层(SCAD)常常被漏诊,但是是导致心肌梗塞(MI)的主要原因之一,尤其是年轻女性。SCAD的远期心血管结局和复发率尚未有过报道。本研究纳入327名非动脉粥样硬化的SCAD患者,对其血管造影特征、血管重建、药物使用、住院情况和长期的心血管事件进行随访。患者的平均年龄是52.5 ± 9.6岁,女性占90.5%(56.9%绝经后)。所有患者均存在心肌梗塞,25.7%患有ST段抬高型心梗,7

自发性冠脉夹层(SCAD)常常被漏诊,但是是导致心肌梗塞(MI)的主要原因之一,尤其是年轻女性。SCAD的远期心血管结局和复发率尚未有过报道。本研究纳入327名非动脉粥样硬化的SCAD患者,对其血管造影特征、血管重建、药物使用、住院情况和长期的心血管事件进行随访。患者的平均年龄是52.5 ± 9.6岁,女性占90.5%(56.9%绝经后)。所有患者均存在心肌梗塞,25.7%患有ST段抬高型心梗,74.3%患有非ST段抬高型心梗,8.9%患有室颤或室性心动过速。随访结果显示,有48.3的患者存在心理压力,62.7%患有肌纤维发育不良,4.9%患有结缔组织疾病,11.9%患有全身性炎症性疾病。大部分患者(83.1%)一开始就接受了药物治疗,16.5%的患者接受了PCI治疗,2.2%的患者接受了冠脉搭桥术治疗。大部分患者在出院后接受阿司匹林和β受体阻滞剂治疗,平均的住院天数是3天,总体不良事件的发生率是7.3%。长期随访的平均时间是3.1年,主要心血管不良事件的发生率是19.9%(死亡率:1.2%,反复心梗:16.8%,卒中:1.2%,血管重建:5.8%)。反复性的SCAD出现在10.4%的

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    2018-06-23 hbwxf
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    2017-08-26 sodoo
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    2017-08-24 1771ae4158m

    学习一下很不错

    0

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