Heart:,高敏心肌肌钙蛋白I是心血管疾病的独立预测因子

2018-05-15 MedSci MedSci原创

高敏心肌肌钙蛋白I(hs-cTnI)是一种预测心血管风险因素的新兴生物标志物,本研究的目的旨在评估hs-cTnI作为预测心血管疾病死亡和预后标志物的可行性,并比较性别之间的差异。本研究纳入了澳大利亚3939名研究对象,并对其血清hs-cTnI进行了检测。分析结果发现,基线水平的hs-cTnI在66.1%的研究对象中是可检测的(>1.2 ng/L),经过20年时间的随访,共有886名对象死亡(

高敏心肌肌钙蛋白I(hs-cTnI)是一种预测心血管风险因素的新兴生物标志物,本研究的目的旨在评估hs-cTnI作为预测心血管疾病死亡和预后标志物的可行性,并比较性别之间的差异。本研究纳入了澳大利亚3939名研究对象,并对其血清hs-cTnI进行了检测。分析结果发现,基线水平的hs-cTnI在66.1%的研究对象中是可检测的(>1.2 ng/L),经过20年时间的随访,共有886名对象死亡(361名死于心血管疾病)和940例心血管疾病事件,经弗拉明汉风险评分变量调整后,hs-cTnI是以下预后的强预测因子:总死亡率(HR (95% CI): 1.16 (1.09 - 1.24))、心血管死亡率(1.33 (1.23 - 1.44))、心血管疾病事件(1.18 (1.11 - 1.25))、冠心病(1.11 (1.03 - 1.20))、心衰(1.44 (1.31 - 1.58))和卒中(1.13 (1.03 - 1.24))。此外,性别不影响hs-cTnI的预测效应。研究结果显示,高敏心肌肌钙蛋白I是致死性和非致死性心血管疾病的独立预测因子。原始出处:Kun Z et al.Hi

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    2018-05-17 zhaojie88
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  5. 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encodeId=d9523155e9ea, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Wed May 16 07:09:43 CST 2018, time=2018-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315391, encodeId=5d5b31539191, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Tue May 15 18:59:52 CST 2018, time=2018-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315332, encodeId=cff03153321c, content=早就是了嘛!, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Tue May 15 11:59:30 CST 2018, time=2018-05-15, status=1, ipAttribution=)]
    2018-05-17 slcumt
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content=早就是了嘛!, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Tue May 15 11:59:30 CST 2018, time=2018-05-15, status=1, ipAttribution=)]
  8. 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content=早就是了嘛!, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Tue May 15 11:59:30 CST 2018, time=2018-05-15, status=1, ipAttribution=)]
    2018-05-16 张新亮1853311252142e2fm

    好文献学习了

    0

  9. 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encodeId=d9523155e9ea, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Wed May 16 07:09:43 CST 2018, time=2018-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315391, encodeId=5d5b31539191, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Tue May 15 18:59:52 CST 2018, time=2018-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315332, encodeId=cff03153321c, content=早就是了嘛!, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Tue May 15 11:59:30 CST 2018, time=2018-05-15, status=1, ipAttribution=)]
    2018-05-15 虈亣靌

    学习一下很不错

    0

  10. 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encodeId=d9523155e9ea, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Wed May 16 07:09:43 CST 2018, time=2018-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315391, encodeId=5d5b31539191, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Tue May 15 18:59:52 CST 2018, time=2018-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315332, encodeId=cff03153321c, content=早就是了嘛!, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Tue May 15 11:59:30 CST 2018, time=2018-05-15, status=1, ipAttribution=)]
    2018-05-15 易水河

    早就是了嘛!

    0

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NAFLD的发病率增加了5倍,特别是在年轻人中发病率更高。MC减弱了NAFLD对死亡的影响,并消除了它对CV疾病的影响。

JAHA:妊娠高血压可增加孕妇心血管疾病发生风险

子癫前期和妊娠期高血压(GH)是最常见的妊娠期高血压疾病。子癫前期被证实与心血管疾病(CVD)发生风险相关,但GH与心血管疾病发生风险的相关性尚未被阐明。本研究纳入了挪威1980年至2009年首次妊娠的617589名妇女,平均随访时间是14.3年。分析结果显示,首次妊娠有GH的妇女出现CVD的风险是无妊娠高血压疾病妇女的1.8倍(95% Cl, 1.7-2.0),当GH联合小于胎龄儿或早产儿时,该

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本研究的目的旨在评估血小板减少(PLT)联合总同型半胱氨酸升高(tHcy)是否会增加首次卒中发生风险,且叶酸治疗能否改善这种风险的增加。本研究纳入了10789名中国高血压成年患者(平均年龄为59.5岁,男性占38%,无卒中和心梗病史),所有患者随机分成依那普利联合叶酸治疗组(n=5408)和依那普利单独治疗组(n=5381),主要终点事件是首次卒中的发生。经过4.2年时间的随访,总共发生了371例

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本研究的目的旨在评估经各种不孕症治疗后出生的活产婴儿发生青紫型先天性心脏病(CCHDs)的风险。本研究纳入了美国2011年至2014年出生的14242267例活产婴儿,其中101494例是经辅助生殖技术(ART)出生的,81242例是经非ART不孕症治疗出生的,CCHDs在ART组、非ART组和自然受孕组出生婴儿的发病率分别是393/100892 (0.39%)、 210/80884 (0.26%

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ST段抬高型心梗(STEMI)女性患者接受的治疗和预后均要差于男性患者。本研究的目的旨在评估男女性STEMI患者在履行STEMI治疗方案前后的治疗和预后差别。研究者于2014年七月列出了一项4步STEMI治疗方案,并对STEMI患者在实施方案前后的PCI前指南指导下的治疗(GDMT)、平均急诊至血管开通时间(D2BT)、院内的不良反应事件和30天死亡率进行了评估和危险分层。最终,共纳入了1272名