CELL HOST MICROBE:喂养方式影响母乳微生物群

2019-02-14 海北 网络

已有的研究显示,母乳含有一个复杂的细菌群落,可以帮助婴儿肠道微生物群的定植。但是至今为止,我们关于母乳微生物群的组成和决定因素还知之甚少。

已有的研究显示,母乳含有一个复杂的细菌群落,可以帮助婴儿肠道微生物群的定植。但是至今为止,我们关于母乳微生物群的组成和决定因素还知之甚少。

最近,在来自CHILD队列的393名母婴双胞胎中,研究人员发现产后3-4个月的乳汁微生物群由反相关的变形菌和厚壁菌门控制,并表现出离散的组成模式。

母乳微生物群的组成和多样性与母性因素(BMI,胎次和分娩方式),母乳喂养实践,以及性别特定的其他母乳成分相关。

因果模型确定母乳喂养模式是母乳微生物群组成的关键决定因素。具体而言,泵提取的母乳始终与多种微生物群参数相关联,包括富集潜在病原体和消耗双歧杆菌。此外,这些数据支持逆行接种假设,其中婴儿口腔影响乳汁微生物群。

总的来说,这些结果确定了人乳微生物群组成的特征和决定因素,对婴儿健康和发育具有潜在影响。


原始出处:

Shirin Moossavi et al. Composition and Variation of the Human Milk Microbiota Are Influenced by Maternal and Early-Life FactorsCell Host & Microbe, 2019; 25 (2): 324 DOI: 10.1016/j.chom.2019.01.011


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    2019-09-09 维他命
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1961428, encodeId=c4f2196142877, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Mon Sep 09 07:32:00 CST 2019, time=2019-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1665072, encodeId=a8a816650e29e, content=<a href='/topic/show?id=c8664008e1a' target=_blank style='color:#2F92EE;'>#喂养#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40087, encryptionId=c8664008e1a, topicName=喂养)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ed425881542, createdName=ms1948154235210413, createdTime=Sat Aug 31 20:32:00 CST 2019, time=2019-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1857755, encodeId=3292185e755e4, content=<a href='/topic/show?id=3f48525849' target=_blank style='color:#2F92EE;'>#CRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5258, encryptionId=3f48525849, topicName=CRO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c30265, createdName=jiafufeng@yaho, createdTime=Tue May 21 13:32:00 CST 2019, time=2019-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1825019, encodeId=630c1825019a8, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Wed Aug 21 17:32:00 CST 2019, time=2019-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1871151, encodeId=d59d18e1151bb, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Thu Nov 28 10:32:00 CST 2019, time=2019-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2084488, encodeId=e7f5208448873, content=<a href='/topic/show?id=61f411e013b' target=_blank style='color:#2F92EE;'>#Micro#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11701, encryptionId=61f411e013b, topicName=Micro)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d59291, createdName=xjy02, createdTime=Thu Mar 14 09:32:00 CST 2019, time=2019-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299603, encodeId=70bd1299603c0, content=<a href='/topic/show?id=7a056349485' target=_blank style='color:#2F92EE;'>#母乳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63494, encryptionId=7a056349485, topicName=母乳)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1b289, createdName=villahu, createdTime=Sat Feb 16 01:32:00 CST 2019, time=2019-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1367773, encodeId=d6d6136e77356, content=<a href='/topic/show?id=2cee50e22c6' target=_blank style='color:#2F92EE;'>#微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50722, encryptionId=2cee50e22c6, topicName=微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3609256, createdName=zhu_jun9837, createdTime=Sat Feb 16 01:32:00 CST 2019, time=2019-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=360614, encodeId=2407360614c5, content=好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eb131638261, createdName=lietome24, createdTime=Thu Feb 14 10:51:29 CST 2019, time=2019-02-14, status=1, ipAttribution=)]
    2019-03-14 xjy02
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    2019-02-16 villahu
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    2019-02-14 lietome24

    好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!

    0

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