BMC Gastroenterology: 内脏脂肪对急性胰腺炎严重程度的影响

2019-06-26 不详 MedSci原创

内脏脂肪与急性胰腺炎(AP)之间的关系尚未完全阐明。本项研究旨在评估内脏脂肪组织(VAT)和骨骼肌组织(VAT / SMT)的比例对AP患者预后的意义。

背景
内脏脂肪与急性胰腺炎(AP)之间的关系尚未完全阐明。本项研究旨在评估内脏脂肪组织(VAT)和骨骼肌组织(VAT / SMT)的比例对AP患者预后的意义。

方法
研究人员收集了从2010年到2017年间306名住院患者纳入了本研究分析。使用未增强的计算机断层扫描(CT)测量VAT,皮下脂肪组织(SAT)和SMT。Cox比例风险模型用于危险因素分析。

结果

与轻度AP(MAP)组相比,严重AP(SAP)和中度重度AP(MSAP)组的VAT和VAT / SMT比率显着更高(p<0.001)。重症监护史,AP严重程度,系统并发症和预后评分与AP患者的VAT和VAT / SMT比值显着相关。VAT的多变量调整风险比(HRs)和身体参数与AP死亡率之间的VAT / SMT比率为1.042(95%可信区间(CI),1.019-1.066)和7.820(95%CI,1.978-30.917) )。

结论
VAT和VAT/SMT比率是AP的独立预后指标。

原始出处:

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    2019-11-10 许安
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