Curr Opin Ophthalmol：医学和硬化剂治疗眼眶淋巴管畸形的研究进展

2019-07-27 MedSci 网络

香港特别行政区香港眼科医院与香港中文大学眼科学与视觉科学系的Lam SC和Yuen HKL近日在Curr Opin Ophthalmol杂志上发表了综述文章。目前，对于眼眶淋巴管畸形没有理想的治疗方法。但自从在治疗中发现新药物以来，已经取得了重大进展，他们系统回顾最近关于新硬化剂和全身用药的证据。

香港特别行政区香港眼科医院与香港中文大学眼科学与视觉科学系的Lam SC和Yuen HKL近日在Curr Opin Ophthalmol杂志上发表了综述文章。目前，对于眼眶淋巴管畸形没有理想的治疗方法。但自从在治疗中发现新药物以来，已经取得了重大进展，他们系统回顾最近关于新硬化剂和全身用药的证据。

传统的硬化剂是OK-432，十四烷基硫酸钠和乙醇。最近的趋势是使用多西环素、博来霉素和平阳霉素。西罗莫司作为一种全身用药已经彻底改变了淋巴管畸形的治疗现状。其他口服药物如普萘洛尔和西地那非目前存在争议。未来的治疗措施可能有靶向淋巴管生成途径的方法，包括抑制血管内皮生长因子和磷脂酰肌醇4,5-二磷酸3-激酶催化亚基等药物。

综上，新药物的开发可以在多模式治疗或单一模式疗法及联合疗法等方面进行，以控制该疾病的发展。

原文出处：

Lam, S.C. and H.K.L. Yuen, Medical and sclerosing agents in the treatment of orbital lymphatic malformations: what's new? Curr Opin Ophthalmol, 2019.

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2019-10-08 shizhenshan

#眼眶淋巴管#

34 0
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2019-08-24 xlwang2691

#硬化剂#

31 0
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2019-07-29 爆笑小医

#畸形#

28 0
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2019-07-29 仁心济世

#研究进展#

30 0
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2019-07-29 amyloid

#淋巴管#

55 0
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2019-07-29 1249842em13(暂无昵称)

#THA#

29 0
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2019-07-29 12498e87m44暂无昵称

#眼眶#

26 0
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2019-07-27 AlexYang

学习

61 0
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2019-07-27 医者仁心5538

学习了

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